Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions
Abstract Cervical cancer remains a major global health concern, with a specially alarming incidence in younger women. Traditional detection techniques such as the Pap smear and colposcopy often lack sensitivity and specificity and are highly dependent on the experience of the gynaecologist. In respo...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-84422-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841559718163644416 |
|---|---|
| author | Carlos Vega Norberto Medina Laura Quintana-Quintana Raquel Leon Himar Fabelo Jorge Rial Alicia Martín Gustavo M. Callico |
| author_facet | Carlos Vega Norberto Medina Laura Quintana-Quintana Raquel Leon Himar Fabelo Jorge Rial Alicia Martín Gustavo M. Callico |
| author_sort | Carlos Vega |
| collection | DOAJ |
| description | Abstract Cervical cancer remains a major global health concern, with a specially alarming incidence in younger women. Traditional detection techniques such as the Pap smear and colposcopy often lack sensitivity and specificity and are highly dependent on the experience of the gynaecologist. In response, this study proposes the use of Hyperspectral Imaging, a pioneering technology that combines traditional imaging with spectroscopy to provide detailed spatial and spectral information. Over a period of six-months, our custom-designed hyperspectral colposcope was used on 62 patients. The gathered data underwent a specialized preprocessing workflow using a PCA-based strategy for unsupervised segmentation of the cervical region. This process extracted spectral signatures from various tissue types, and our subsequent statistical analysis highlighted its ability to detect differences and alterations in the cervical tissue. This offers a promising avenue for improving the precision of cervical lesion diagnosis. |
| format | Article |
| id | doaj-art-249a58a6d6c0448db70e5334493eeaf9 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-249a58a6d6c0448db70e5334493eeaf92025-01-05T12:14:31ZengNature PortfolioScientific Reports2045-23222025-01-0115111510.1038/s41598-024-84422-zFeasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesionsCarlos Vega0Norberto Medina1Laura Quintana-Quintana2Raquel Leon3Himar Fabelo4Jorge Rial5Alicia Martín6Gustavo M. Callico7Research Institute for Applied Microelectronics (IUMA), University of Las Palmas de Gran Canaria (ULPGC)Complejo Hospitalario Universitario Insular Materno Infantil (CHUIMI), Servicio Canario de Salud (SCS)Research Institute for Applied Microelectronics (IUMA), University of Las Palmas de Gran Canaria (ULPGC)Research Institute for Applied Microelectronics (IUMA), University of Las Palmas de Gran Canaria (ULPGC)Research Institute for Applied Microelectronics (IUMA), University of Las Palmas de Gran Canaria (ULPGC)OPTOMIC ESPAÑA S.AComplejo Hospitalario Universitario Insular Materno Infantil (CHUIMI), Servicio Canario de Salud (SCS)Research Institute for Applied Microelectronics (IUMA), University of Las Palmas de Gran Canaria (ULPGC)Abstract Cervical cancer remains a major global health concern, with a specially alarming incidence in younger women. Traditional detection techniques such as the Pap smear and colposcopy often lack sensitivity and specificity and are highly dependent on the experience of the gynaecologist. In response, this study proposes the use of Hyperspectral Imaging, a pioneering technology that combines traditional imaging with spectroscopy to provide detailed spatial and spectral information. Over a period of six-months, our custom-designed hyperspectral colposcope was used on 62 patients. The gathered data underwent a specialized preprocessing workflow using a PCA-based strategy for unsupervised segmentation of the cervical region. This process extracted spectral signatures from various tissue types, and our subsequent statistical analysis highlighted its ability to detect differences and alterations in the cervical tissue. This offers a promising avenue for improving the precision of cervical lesion diagnosis.https://doi.org/10.1038/s41598-024-84422-z |
| spellingShingle | Carlos Vega Norberto Medina Laura Quintana-Quintana Raquel Leon Himar Fabelo Jorge Rial Alicia Martín Gustavo M. Callico Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions Scientific Reports |
| title | Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions |
| title_full | Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions |
| title_fullStr | Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions |
| title_full_unstemmed | Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions |
| title_short | Feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions |
| title_sort | feasibility study of hyperspectral colposcopy as a novel tool for detecting precancerous cervical lesions |
| url | https://doi.org/10.1038/s41598-024-84422-z |
| work_keys_str_mv | AT carlosvega feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions AT norbertomedina feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions AT lauraquintanaquintana feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions AT raquelleon feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions AT himarfabelo feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions AT jorgerial feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions AT aliciamartin feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions AT gustavomcallico feasibilitystudyofhyperspectralcolposcopyasanoveltoolfordetectingprecancerouscervicallesions |