Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers

Longitudinal association of peripheral blood DNA methylation with liver fat content: distinguishing between predictors and biomarkers

Abstract Background Alterations in DNA methylation (DNAm) have been observed in patients with fatty liver, but whether they are cause or consequence remains unknown. The study aimed to investigate longitudinal association of epigenome-wide DNAm with liver fat content (LFC) in Chinese participants, a...

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Bibliographic Details
Main Authors: Hailuan Zeng, Wenran Li, Mingfeng Xia, Jieyu Ge, Hui Ma, Lingyan Chen, Baishen Pan, Huandong Lin, Sijia Wang, Xin Gao
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Lipids in Health and Disease
Subjects:
Liver fat content
DNA methylation
Cross-lagged panel analysis
Longitudinal study
Online Access:https://doi.org/10.1186/s12944-024-02304-9
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