Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion
Objective To screen the prognostic influencing factors of patients with endovascular treatment for acute basilar artery occlusion (ABAO⁃EVT). Methods The baseline, clinical and follow⁃up data of 215 patients with ABAO⁃EVT from October 2017 to August 2022 in The First Affiliated Hospital of Universi...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tianjin Huanhu Hospital
2024-11-01
|
| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/2951 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846135949641121792 |
|---|---|
| author | HAO Peng TAO Chun⁃rong JING Xiao⁃zhong LI Rui LUO Cong HU Wei |
| author_facet | HAO Peng TAO Chun⁃rong JING Xiao⁃zhong LI Rui LUO Cong HU Wei |
| author_sort | HAO Peng |
| collection | DOAJ |
| description | Objective To screen the prognostic influencing factors of patients with endovascular treatment for acute basilar artery occlusion (ABAO⁃EVT). Methods The baseline, clinical and follow⁃up data of 215 patients with ABAO⁃EVT from October 2017 to August 2022 in The First Affiliated Hospital of
University of Science and Technology of China, Linyi People's Hospital of Shandong and Maoming People's Hospital of Guangdong were retrospectively collected, including sex, age, stroke or transient ischemic attack (TIA), hypertension, diabetes, coronary heart disease, atrial fibrillation, smoking and drinking history, National Institutes of Health Stroke Scale (NIHSS) score, intravenous thrombolysis, first pass effect, times of
embolectomy, extended Thrombolysis in Cerebral Infarction (eTICI), and modified Rankin Scale (mRS) score 90 d after operation. According to the 90 d mRS score, the patients were divided into 2 groups: good prognosis group (mRS score 0-3, n = 93) and poor prognosis group (mRS score 4-6, n = 122). Univariate and multivariate stepwise Logistic regression analyses were used to screen the neurological prognostic influencing factors of ABAO ⁃ EVT patients 90 d after operation. Results Logistic regression analysis showed that the baseline NIHSS score increased was a risk factor for poor prognosis of ABAO⁃EVT patients (aOR = 0.936, 95%CI: 0.907-0.965, P = 0.000; aOR = 0.940, 95%CI: 0.910-0.970, P = 0.000), with the first pass effect (aOR = 5.752, 95%CI: 2.875-11.508; P = 0.000), eTICI grade 2c-3 (aOR = 7.113, 95%CI: 3.665-13.805; P = 0.000) were protective factors for good prognosis. Conclusions Low baseline NIHSS score, first pass effect and reperfusion level of eTICI 2c-3 are all protective factors for good neurological prognosis of ABAO⁃EVT patients. |
| format | Article |
| id | doaj-art-244744d80bae45308ca35ce16dba5740 |
| institution | Kabale University |
| issn | 1672-6731 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj-art-244744d80bae45308ca35ce16dba57402024-12-09T09:44:42ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312024-11-01241192096DOI:10.3969/j.issn.1672⁃6731.2024.11.008Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusionHAO Peng0TAO Chun⁃rong1JING Xiao⁃zhong2LI Rui3LUO Cong4HU Wei5Department of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui, ChinaDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui, ChinaDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui, ChinaDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui, ChinaDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui, ChinaDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui, ChinaObjective To screen the prognostic influencing factors of patients with endovascular treatment for acute basilar artery occlusion (ABAO⁃EVT). Methods The baseline, clinical and follow⁃up data of 215 patients with ABAO⁃EVT from October 2017 to August 2022 in The First Affiliated Hospital of University of Science and Technology of China, Linyi People's Hospital of Shandong and Maoming People's Hospital of Guangdong were retrospectively collected, including sex, age, stroke or transient ischemic attack (TIA), hypertension, diabetes, coronary heart disease, atrial fibrillation, smoking and drinking history, National Institutes of Health Stroke Scale (NIHSS) score, intravenous thrombolysis, first pass effect, times of embolectomy, extended Thrombolysis in Cerebral Infarction (eTICI), and modified Rankin Scale (mRS) score 90 d after operation. According to the 90 d mRS score, the patients were divided into 2 groups: good prognosis group (mRS score 0-3, n = 93) and poor prognosis group (mRS score 4-6, n = 122). Univariate and multivariate stepwise Logistic regression analyses were used to screen the neurological prognostic influencing factors of ABAO ⁃ EVT patients 90 d after operation. Results Logistic regression analysis showed that the baseline NIHSS score increased was a risk factor for poor prognosis of ABAO⁃EVT patients (aOR = 0.936, 95%CI: 0.907-0.965, P = 0.000; aOR = 0.940, 95%CI: 0.910-0.970, P = 0.000), with the first pass effect (aOR = 5.752, 95%CI: 2.875-11.508; P = 0.000), eTICI grade 2c-3 (aOR = 7.113, 95%CI: 3.665-13.805; P = 0.000) were protective factors for good prognosis. Conclusions Low baseline NIHSS score, first pass effect and reperfusion level of eTICI 2c-3 are all protective factors for good neurological prognosis of ABAO⁃EVT patients.http://www.cjcnn.org/index.php/cjcnn/article/view/2951ischemic stroke; basilar artery; thrombectomy; prognosis; reperfusion; risk factors; logistic models; multicenter study |
| spellingShingle | HAO Peng TAO Chun⁃rong JING Xiao⁃zhong LI Rui LUO Cong HU Wei Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion Chinese Journal of Contemporary Neurology and Neurosurgery ischemic stroke; basilar artery; thrombectomy; prognosis; reperfusion; risk factors; logistic models; multicenter study |
| title | Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion |
| title_full | Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion |
| title_fullStr | Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion |
| title_full_unstemmed | Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion |
| title_short | Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion |
| title_sort | multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion |
| topic | ischemic stroke; basilar artery; thrombectomy; prognosis; reperfusion; risk factors; logistic models; multicenter study |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/2951 |
| work_keys_str_mv | AT haopeng multicenterstudyonprognosticinfluencingfactorsofendovasculartreatmentforacutebasilararteryocclusion AT taochunrong multicenterstudyonprognosticinfluencingfactorsofendovasculartreatmentforacutebasilararteryocclusion AT jingxiaozhong multicenterstudyonprognosticinfluencingfactorsofendovasculartreatmentforacutebasilararteryocclusion AT lirui multicenterstudyonprognosticinfluencingfactorsofendovasculartreatmentforacutebasilararteryocclusion AT luocong multicenterstudyonprognosticinfluencingfactorsofendovasculartreatmentforacutebasilararteryocclusion AT huwei multicenterstudyonprognosticinfluencingfactorsofendovasculartreatmentforacutebasilararteryocclusion |