Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors

Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors

Abstract Legionella pneumophila utilizes the Dot/Icm type IVB secretion system to deliver hundreds of effector proteins inside eukaryotic cells to ensure intracellular replication. Our understanding of the molecular functions of the largest pathogenic arsenal known to the bacterial world remains inc...

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Bibliographic Details
Main Authors: Deepak T Patel, Peter J Stogios, Lukasz Jaroszewski, Malene L Urbanus, Mayya Sedova, Cameron Semper, Cathy Le, Abraham Takkouche, Keita Ichii, Julie Innabi, Dhruvin H Patel, Alexander W Ensminger, Adam Godzik, Alexei Savchenko
Format: Article
Language:English
Published: Springer Nature 2024-11-01
Series:Molecular Systems Biology
Subjects:
Bacterial Effectors
Legionella pneumophila
Protein Modeling
Yeast Toxicity
Cryptic Domains
Online Access:https://doi.org/10.1038/s44320-024-00076-z
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