Properties of Maxentropic DNA Synthesis Codes

Low-weight codes have been proposed for efficiently synthesizing deoxyribonucleic acid (DNA) for massive data storage, where a multiple of DNA strands are synthesized in parallel. We report on the redundancy and information rate of maxentropic low-weight codes for asymptotically large codeword lengt...

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Main Authors: Kees Schouhamer Immink, Jos H. Weber, Kui Cai
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Entropy
Subjects:
Online Access:https://www.mdpi.com/1099-4300/26/12/1028
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author Kees Schouhamer Immink
Jos H. Weber
Kui Cai
author_facet Kees Schouhamer Immink
Jos H. Weber
Kui Cai
author_sort Kees Schouhamer Immink
collection DOAJ
description Low-weight codes have been proposed for efficiently synthesizing deoxyribonucleic acid (DNA) for massive data storage, where a multiple of DNA strands are synthesized in parallel. We report on the redundancy and information rate of maxentropic low-weight codes for asymptotically large codeword length. We compare the performance of low-complexity nibble replacement (NR) codes, which are designed to minimize the synthesis time, with the performance of maxentropic low-weight codes. Finally, the asymptotic redundancy and information rate of codes with a runlength limitation are investigated.
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spelling doaj-art-241c4bb05fe14727be2c34fd6273dc962024-12-27T14:24:58ZengMDPI AGEntropy1099-43002024-11-012612102810.3390/e26121028Properties of Maxentropic DNA Synthesis CodesKees Schouhamer Immink0Jos H. Weber1Kui Cai2Turing Machines Inc., Willemskade 15, 3016 DK Rotterdam, The NetherlandsDepartment of Applied Mathematics, Delft University of Technology, 2628 CD Delft, The NetherlandsScience, Mathematics and Technology Cluster, Singapore University of Technology and Design (SUTD), 8 Somapah Rd, Singapore 487372, SingaporeLow-weight codes have been proposed for efficiently synthesizing deoxyribonucleic acid (DNA) for massive data storage, where a multiple of DNA strands are synthesized in parallel. We report on the redundancy and information rate of maxentropic low-weight codes for asymptotically large codeword length. We compare the performance of low-complexity nibble replacement (NR) codes, which are designed to minimize the synthesis time, with the performance of maxentropic low-weight codes. Finally, the asymptotic redundancy and information rate of codes with a runlength limitation are investigated.https://www.mdpi.com/1099-4300/26/12/1028code designDNA synthesislow-weight codemaximum runlength constraintnibble replacement (NR) code
spellingShingle Kees Schouhamer Immink
Jos H. Weber
Kui Cai
Properties of Maxentropic DNA Synthesis Codes
Entropy
code design
DNA synthesis
low-weight code
maximum runlength constraint
nibble replacement (NR) code
title Properties of Maxentropic DNA Synthesis Codes
title_full Properties of Maxentropic DNA Synthesis Codes
title_fullStr Properties of Maxentropic DNA Synthesis Codes
title_full_unstemmed Properties of Maxentropic DNA Synthesis Codes
title_short Properties of Maxentropic DNA Synthesis Codes
title_sort properties of maxentropic dna synthesis codes
topic code design
DNA synthesis
low-weight code
maximum runlength constraint
nibble replacement (NR) code
url https://www.mdpi.com/1099-4300/26/12/1028
work_keys_str_mv AT keesschouhamerimmink propertiesofmaxentropicdnasynthesiscodes
AT joshweber propertiesofmaxentropicdnasynthesiscodes
AT kuicai propertiesofmaxentropicdnasynthesiscodes