Impact of Exercise on Tramadol-Conditioned Place Preference
Background: Tramadol (TRA) is an opioid that is used to manage moderate to severe pain. Long-term use of TRA can lead to the development of opioid use disorder. Objectives: This study investigates the role of forced exercise in reducing TRA-seeking behavior. Methods: Adult male rats (240–260 g) were...
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Main Authors: | Haneen Amawi, Alaa M. Hammad, Aseel Abdullah Ibrahim, Nosyba Alsbih, Frank Scott Hall, Fawaz Alasmari, Bahaa Al-Trad |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-01-01
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Series: | Brain Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3425/15/1/89 |
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