The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications

The study of the state of carbohydrate and lipid metabolism in 47 children and adolescents with type 1 diabetes mellitus showed a progressive decrease in residual insulin secretion and insulin-binding activity of lymphocytes against the background of metabolic disorders of fatty acids, which are ris...

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Main Authors: N. P. Mikaelyan, A. V. Shestopalov, A. V. Mikaelyan, A. E. Gurina, V. V. Smirnov
Format: Article
Language:Russian
Published: Open Systems Publication 2021-06-01
Series:Лечащий Врач
Subjects:
Online Access:https://journal.lvrach.ru/jour/article/view/353
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author N. P. Mikaelyan
A. V. Shestopalov
A. V. Mikaelyan
A. E. Gurina
V. V. Smirnov
author_facet N. P. Mikaelyan
A. V. Shestopalov
A. V. Mikaelyan
A. E. Gurina
V. V. Smirnov
author_sort N. P. Mikaelyan
collection DOAJ
description The study of the state of carbohydrate and lipid metabolism in 47 children and adolescents with type 1 diabetes mellitus showed a progressive decrease in residual insulin secretion and insulin-binding activity of lymphocytes against the background of metabolic disorders of fatty acids, which are risk factors for severe course of the disease with the rapid development of hypoxia and other diabetic complications, including functional disorders in the digestive system.
format Article
id doaj-art-23f8b59d706d4c65943f2b2e8f765d3e
institution Kabale University
issn 1560-5175
2687-1181
language Russian
publishDate 2021-06-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-23f8b59d706d4c65943f2b2e8f765d3e2025-08-20T03:42:34ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0106352The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complicationsN. P. Mikaelyan0A. V. Shestopalov1A. V. Mikaelyan2A. E. Gurina3V. V. Smirnov4ФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФГБУЗ МО МОНИКИ им. М. Ф. ВладимирскогоФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФФГБОУ ВО РНИМУ им. Н. И. Пирогова МЗ РФThe study of the state of carbohydrate and lipid metabolism in 47 children and adolescents with type 1 diabetes mellitus showed a progressive decrease in residual insulin secretion and insulin-binding activity of lymphocytes against the background of metabolic disorders of fatty acids, which are risk factors for severe course of the disease with the rapid development of hypoxia and other diabetic complications, including functional disorders in the digestive system.https://journal.lvrach.ru/jour/article/view/353fatty acidsinsulin binding activityinsulin secretionc-peptidehypoxialactacidemia
spellingShingle N. P. Mikaelyan
A. V. Shestopalov
A. V. Mikaelyan
A. E. Gurina
V. V. Smirnov
The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications
Лечащий Врач
fatty acids
insulin binding activity
insulin secretion
c-peptide
hypoxia
lactacidemia
title The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications
title_full The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications
title_fullStr The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications
title_full_unstemmed The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications
title_short The metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications
title_sort metabolism of fatty acids and insulin secretion in children with type 1 diabetes mellitus and its complications
topic fatty acids
insulin binding activity
insulin secretion
c-peptide
hypoxia
lactacidemia
url https://journal.lvrach.ru/jour/article/view/353
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