Emergence of cefiderocol resistance during therapy in NDM-5–producing Klebsiella pneumoniae isolates harboring siderophore receptors mutations

Emergence of cefiderocol resistance during therapy in NDM-5–producing Klebsiella pneumoniae isolates harboring siderophore receptors mutations

Cefiderocol, a siderophore-conjugated cephalosporine, is a promising drug used to treat infection with carbapenem-resistant gram-negative bacteria. Here, we report a case of pneumonia induced by multiple gram-negative pathogens, including a carbapenem-resistant Klebsiella pneumoniae developing cefid...

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Bibliographic Details
Main Authors: Luc Deroche, Albane Rozenholc, François Arrivé, Jean-Philippe Martellosio, Gwenaël Le Moal, Arnaud W. Thille, Olivier Barraud, Sandrine Marchand, Julien M. Buyck
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:International Journal of Infectious Diseases
Subjects:
Cefiderocol
Antibiotic resistance
Klebsiella pneumoniae
Siderophore receptor
WGS
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224003965
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