Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy
Antibiotic therapy has been a common method for treating bacterial infections over the past century, but with the rise in bacterial resistance caused by antibiotic abuse, better control and more rational use of antibiotics have been increasingly demanded. At the same time, a journey to explore alter...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-12-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/11/12/1278 |
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| author | Meng Wang Yue Wang Geyun Chen Hongyu Gao Qiang Peng |
| author_facet | Meng Wang Yue Wang Geyun Chen Hongyu Gao Qiang Peng |
| author_sort | Meng Wang |
| collection | DOAJ |
| description | Antibiotic therapy has been a common method for treating bacterial infections over the past century, but with the rise in bacterial resistance caused by antibiotic abuse, better control and more rational use of antibiotics have been increasingly demanded. At the same time, a journey to explore alternatives to antibiotic therapies has also been undertaken. Chitosan and its derivatives, materials with good biocompatibility, biodegradability, and excellent antibacterial properties, have garnered significant attention, and more and more studies on chitosan and its derivatives have been conducted in recent years. In this work, we aim to elucidate the biological properties of chitosan and its derivatives and to track their clinical applications, as well as to propose issues that need to be addressed and possible solutions to further their future development and application. |
| format | Article |
| id | doaj-art-23324d2d208d48a98adb7682cef612c8 |
| institution | Kabale University |
| issn | 2306-5354 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj-art-23324d2d208d48a98adb7682cef612c82024-12-27T14:11:43ZengMDPI AGBioengineering2306-53542024-12-011112127810.3390/bioengineering11121278Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial TherapyMeng Wang0Yue Wang1Geyun Chen2Hongyu Gao3Qiang Peng4State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaState Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, ChinaAntibiotic therapy has been a common method for treating bacterial infections over the past century, but with the rise in bacterial resistance caused by antibiotic abuse, better control and more rational use of antibiotics have been increasingly demanded. At the same time, a journey to explore alternatives to antibiotic therapies has also been undertaken. Chitosan and its derivatives, materials with good biocompatibility, biodegradability, and excellent antibacterial properties, have garnered significant attention, and more and more studies on chitosan and its derivatives have been conducted in recent years. In this work, we aim to elucidate the biological properties of chitosan and its derivatives and to track their clinical applications, as well as to propose issues that need to be addressed and possible solutions to further their future development and application.https://www.mdpi.com/2306-5354/11/12/1278antimicrobialdrug deliverybioactive materialsantibioticsbacterium |
| spellingShingle | Meng Wang Yue Wang Geyun Chen Hongyu Gao Qiang Peng Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy Bioengineering antimicrobial drug delivery bioactive materials antibiotics bacterium |
| title | Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy |
| title_full | Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy |
| title_fullStr | Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy |
| title_full_unstemmed | Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy |
| title_short | Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy |
| title_sort | chitosan based multifunctional biomaterials as active agents or delivery systems for antibacterial therapy |
| topic | antimicrobial drug delivery bioactive materials antibiotics bacterium |
| url | https://www.mdpi.com/2306-5354/11/12/1278 |
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