Lactobacillus reuteri DSM 17,938 ameliorates LPS-induced depression-like and anxiety-like behaviors by modulating gut microbiota and brain metabolic function

Lactobacillus reuteri DSM 17,938 ameliorates LPS-induced depression-like and anxiety-like behaviors by modulating gut microbiota and brain metabolic function

Abstract Background Lactobacillus reuteri DSM 17,938 exhibits antidepressant and anxiolytic potential. The purpose of this study is to validate the effects of L. reuteri DSM 17,938 and preliminarily explore its underlying antidepressant and anxiolytic mechanisms, thereby providing a general directio...

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Bibliographic Details
Main Authors: Xiaolong Mo, Siyi Guo, Dian He, Qisheng Cheng, Yichun Yang, Haiyang Wang, Yikun Ren, Lanxiang Liu, Peng Xie
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Gut Pathogens
Subjects:
Depression
LPS
Lactobacillus reuteri DSM 17938
Metagenomics
Metabolomics
Online Access:https://doi.org/10.1186/s13099-025-00739-8
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