Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach
Osteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A...
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| Format: | Article |
| Language: | English |
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Romanian Association of Balneology, Editura Balneara
2025-12-01
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| Series: | Balneo and PRM Research Journal |
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| Online Access: | http://bioclima.ro/Balneo756.pdf |
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| author | Oana Raluca Antonescu Sinziana Calina Silisteanu Alina Cristiana Venter Mihaela Racheriu Irina Elena Antonescu Enikő Nemes-Nagy |
| author_facet | Oana Raluca Antonescu Sinziana Calina Silisteanu Alina Cristiana Venter Mihaela Racheriu Irina Elena Antonescu Enikő Nemes-Nagy |
| author_sort | Oana Raluca Antonescu |
| collection | DOAJ |
| description | Osteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A retrospective study was conducted, which included an initial cohort of 243 patients hospitalized between January 2023 and December 2023 at the County Emergency Hospital of Sibiu, Clinical Endocrinology Department ; Study results suggest that assessment of bone mineral density (BMD) remains a primary standard in the diagnosis of osteoporosis, as measured by T and Z scores from DXA densitometry. However, biomarkers such as total calcium, ionic calcium, vitamin D, phosphorus, PTH and bone degradation markers (e.g. Beta Crosslaps) play a significant role in assessing bone metabolism and identifying fracture risk; The study highlights the importance of screening in postmenopausal women and the need for calcium and vitamin D supplementation in patients with osteoporosis or osteopenia |
| format | Article |
| id | doaj-art-23141b9e2f4d413889c678266627641d |
| institution | Kabale University |
| issn | 2734-8458 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Romanian Association of Balneology, Editura Balneara |
| record_format | Article |
| series | Balneo and PRM Research Journal |
| spelling | doaj-art-23141b9e2f4d413889c678266627641d2025-01-13T14:09:03ZengRomanian Association of Balneology, Editura BalnearaBalneo and PRM Research Journal2734-84582025-12-0115475610.12680/balneo.2024.756Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approachOana Raluca Antonescu0Sinziana Calina Silisteanu1Alina Cristiana Venter2Mihaela Racheriu3Irina Elena Antonescu4Enikő Nemes-Nagy5Faculty of Medicine, Lucian Blaga University Sibiu, 550169 Sibiu, Romania; Doctoral School, Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Tech-nology of Târgu-Mureș, Romania; Doctoral School, Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu-Mureș, RomaniaFaculty of Medicine and Biological Sciences, "Ștefan cel Mare" University of Suceava, Romania; Railway Hospital Iasi - Specialty Ambulatory of SuceavaDepartment of Morphologycal Sciences, University of Oradea, 410081 Oradea, RomaniaFaculty of Medicine, Lucian Blaga University Sibiu, 550169 Sibiu, Romania; Doctoral School, Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Tech-nology of Târgu-Mureș, Romania; Faculty of Medicine, Lucian Blaga University Sibiu, 550169 Sibiu, Romania; Clinical County Emergency Hospital Sibiu, 550245 Sibiu, RomaniaFaculty of Medicine, Lucian Blaga University Sibiu, 550169 Sibiu, Romania; Clinical County Emergency Hospital Sibiu, 550245 Sibiu, Romania; Doctoral School, Lucian Blaga University Sibiu, 550169 Sibiu, Romania; Clinical County Emer-gency Hospital Sibiu, 550245 Sibiu, RomaniaDepartment of Chemistry and Medical Biochemistry, Faculty of Medicine in English, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu-Mureș, 540142 Târgu-Mureș, RomaniaOsteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A retrospective study was conducted, which included an initial cohort of 243 patients hospitalized between January 2023 and December 2023 at the County Emergency Hospital of Sibiu, Clinical Endocrinology Department ; Study results suggest that assessment of bone mineral density (BMD) remains a primary standard in the diagnosis of osteoporosis, as measured by T and Z scores from DXA densitometry. However, biomarkers such as total calcium, ionic calcium, vitamin D, phosphorus, PTH and bone degradation markers (e.g. Beta Crosslaps) play a significant role in assessing bone metabolism and identifying fracture risk; The study highlights the importance of screening in postmenopausal women and the need for calcium and vitamin D supplementation in patients with osteoporosis or osteopeniahttp://bioclima.ro/Balneo756.pdfosteoporosisbiomarkersscreeningpostmenopausal women |
| spellingShingle | Oana Raluca Antonescu Sinziana Calina Silisteanu Alina Cristiana Venter Mihaela Racheriu Irina Elena Antonescu Enikő Nemes-Nagy Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach Balneo and PRM Research Journal osteoporosis biomarkers screening postmenopausal women |
| title | Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach |
| title_full | Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach |
| title_fullStr | Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach |
| title_full_unstemmed | Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach |
| title_short | Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach |
| title_sort | comparative analysis of paraclinical parameters in the assessment of osteoporosis an integrative approach |
| topic | osteoporosis biomarkers screening postmenopausal women |
| url | http://bioclima.ro/Balneo756.pdf |
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