Comparative analysis of paraclinical parameters in the assessment of osteoporosis: an integrative approach
Osteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Romanian Association of Balneology, Editura Balneara
2025-12-01
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| Series: | Balneo and PRM Research Journal |
| Subjects: | |
| Online Access: | http://bioclima.ro/Balneo756.pdf |
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| Summary: | Osteoporosis is the most common metabolic bone disease with serious physical, psychosocial and economic consequences. It is a chronic, asymptomatic, progressive disease with multifactorial aetiology, characterized by reduced bone mineral density and microarchitectural deterioration of bone tissue; A retrospective study was conducted, which included an initial cohort of 243 patients hospitalized between January 2023 and December 2023 at the County Emergency Hospital of Sibiu, Clinical Endocrinology Department ; Study results suggest that assessment of bone mineral density (BMD) remains a primary standard in the diagnosis of osteoporosis, as measured by T and Z scores from DXA densitometry. However, biomarkers such as total calcium, ionic calcium, vitamin D, phosphorus, PTH and bone degradation markers (e.g. Beta Crosslaps) play a significant role in assessing bone metabolism and identifying fracture risk; The study highlights the importance of screening in postmenopausal women and the need for calcium and vitamin D supplementation in patients with osteoporosis or osteopenia |
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| ISSN: | 2734-8458 |