Simultaneous and Direct Determination of Vancomycin and Cephalexin in Human Plasma by Using HPLC-DAD Coupled with Second-Order Calibration Algorithms

A simple, rapid, and sensitive method for the simultaneous determination of vancomycin and cephalexin in human plasma was developed by using HPLC-DAD with second-order calibration algorithms. Instead of a completely chromatographic separation, mathematical separation was performed by using two trili...

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Bibliographic Details
Main Authors: Le-Qian Hu, Chun-Ling Yin, Ya-Hui Du, Zhi-Peng Zeng
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2012/256963
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