Therapeutic potential of sulforaphane: modulation of NRF2-mediated PI3/AKT/mTOR pathway in oral fibrosis

Oral Submucous Fibrosis is a potentially malignant disorder caused by habitual areca nut chewing, which contributes to the dispersion of active alkaloids into subepithelial tissues, stimulating excessive extracellular matrix deposition. Various treatment modalities are available; however, their eff...

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Bibliographic Details
Main Authors: Pooja Narain Adtani, Rajasekaran Subbarayan, Rupendra Shrestha, Walid Elsayed
Format: Article
Language:English
Published: Universidade Estadual Paulista 2024-04-01
Series:Brazilian Dental Science
Online Access:https://ojs.ict.unesp.br/index.php/cob/article/view/4172
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