Randomised, multicentre, placebo-controlled trial of fenofibrate for treatment of diabetic macular oedema with economic evaluation (FORTE study): study protocol for a randomised control trial

Randomised, multicentre, placebo-controlled trial of fenofibrate for treatment of diabetic macular oedema with economic evaluation (FORTE study): study protocol for a randomised control trial

Introduction Diabetic macular oedema (DMO), a serious ocular complication of diabetic retinopathy (DR), is a leading cause of vision impairment worldwide. If left untreated or inadequately treated, DMO can lead to irreversible vision loss and blindness. Intravitreal injections using antivascular end...

Full description

Saved in:

Bibliographic Details
Main Authors:	Gerald Liew, Paul Mitchell, Bamini Gopinath, Helen Nguyen, Richard Kha
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2024-12-01
Series:	BMJ Open
Online Access:	https://bmjopen.bmj.com/content/14/12/e089518.full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

FTACMT study protocol: a multicentre, double-blind, randomised, placebo-controlled trial of faecal microbiota transplantation for autism spectrum disorder
by: Li Ling, et al.
Published: (2022-01-01)

The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled multicentre clinical trial
by: Toby M Maher, et al.
Published: (2025-02-01)

Trial of alginates in throat symptoms: protocol for a pragmatic, multicentre, placebo controlled, double blind, parallel, randomised controlled trial of liquid alginate (Gaviscon Advance) for the treatment of persistent throat symptoms
by: David Hamilton, et al.
Published: (2025-01-01)

FAecal micRobiota transplantation in primary sclerosinG chOlangitis (FARGO): study protocol for a randomised, multicentre, phase IIa, placebo-controlled trial
by: Laith Alrubaiy, et al.
Published: (2025-01-01)

Efficacy and safety of jaktinib hydrochloride tablets in active axial spondyloarthritis: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial
by: Xiaomei Li, et al.
Published: (2025-01-01)

Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial
by: Phillip Knebel, et al.
Published: (2020-09-01)

Melatonin supplementation for the treatment of infantile spasms: protocol for a randomised placebo-controlled triple-blind trial
by: Jing Wang, et al.
Published: (2022-07-01)

Isosorbide mononitrate for preinduction cervical ripening at or post-term pregnancy: randomised placebo-controlled clinical trial
by: Ramy Mohamed El-Naggar, et al.
Published: (2025-01-01)

Risperidone versus placebo for aggression following traumatic brain injury: a feasibility randomised controlled trial
by: Paul Bassett, et al.
Published: (2020-09-01)

Correction: Efficacy and safety of jaktinib hydrochloride tablets in active axial spondyloarthritis: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial
Published: (2025-01-01)

Systematic comparison of Mendelian randomisation studies and randomised controlled trials using electronic databases
by: Jie Zheng, et al.
Published: (2023-09-01)

Optimising Access Surgery in Senior Haemodialysis Patients (OASIS): study protocol for a multicentre randomised controlled trial
by: Patrick WHE Vriens, et al.
Published: (2022-02-01)

Thymosin alpha 1 in the prevention of infected pancreatic necrosis following acute necrotising pancreatitis (TRACE trial): protocol of a multicentre, randomised, double-blind, placebo-controlled, parallel-group trial
by: Tao Chen, et al.
Published: (2020-09-01)

ImmunoglobuliN in the Treatment of Encephalitis (IgNiTE): protocol for a multicentre randomised controlled trial
by: R Kneen, et al.
Published: (2016-11-01)

Effect of electroacupuncture on discomfort in patients undergoing colonoscopy: protocol for a multicentre, randomised, controlled clinical trial
by: Chao Lin, et al.
Published: (2024-12-01)

Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb)
by: Hiroaki Tanaka, et al.
Published: (2022-06-01)

Electroacupuncture for mild-to-moderate dry eye: study protocol for a multicentre, randomised, single-blind, sham-controlled trial
by: Yue Zhao, et al.
Published: (2023-12-01)

Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal)
by: Eleri Adams, et al.
Published: (2022-07-01)

Effects of photobiomodulation therapy in patients with chronic non-specific low back pain: protocol for a randomised placebo-controlled trial
by: Lucíola da Cunha Menezes Costa, et al.
Published: (2017-10-01)

Effectiveness of a personalised self-management intervention for people living with long covid (Listen trial): pragmatic, multicentre, parallel group, randomised controlled trial
by: Fiona Jones, et al.
Published: (2025-01-01)

Efficacy and safety of edoxaban in patients with chronic thromboembolic pulmonary hypertension: protocol for a multicentre, randomised, warfarin-controlled, parallel group trial - KABUKI trial
by: Keiichi Fukuda, et al.
Published: (2022-07-01)

Randomised controlled trial of topical kanuka honey for the treatment of rosacea
by: James Fingleton, et al.
Published: (2015-06-01)

Parallel-group, randomised, controlled, non-inferiority trial of high-flow nasal cannula versus non-invasive ventilation for emergency patients with acute cardiogenic pulmonary oedema: study protocol
by: Apichaya Monsomboon, et al.
Published: (2022-07-01)

Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment
by: Annabelle M Belcher, et al.
Published: (2019-06-01)

Web-based mindfulness and skills-based distress reduction for patients with cancer: study protocol of the multicentre, randomised, controlled confirmatory intervention trial Reduct
by: Dirk Schadendorf, et al.
Published: (2022-06-01)

Depression screening using patient-targeted feedback in general practices: study protocol of the German multicentre GET.FEEDBACK.GP randomised controlled trial
by: Joachim Szecsenyi, et al.
Published: (2020-09-01)

Does semaglutide reduce alcohol intake in Danish patients with alcohol use disorder and comorbid obesity? Trial protocol of a randomised, double-blinded, placebo-controlled clinical trial (the SEMALCO trial)
by: Jens Juul Holst, et al.
Published: (2025-01-01)

Effect of folic acid supplementation on diminished ovarian reserve: study protocol of a single-centre, open-label, randomised, placebo-controlled clinical trial
by: Yan Wang, et al.
Published: (2022-07-01)

A systematic review of randomised controlled trials on topical nasal steroids
by: Chiara Zeroli, et al.
Published: (2024-04-01)

International REACH forgiveness intervention: a multisite randomised controlled trial
by: Tyler J Vanderweele, et al.
Published: (2024-04-01)

Therapeutic alliance in a stepped digital psychosocial intervention for breast cancer patients: findings from a multicentre randomised controlled trial
by: Aida Flix-Valle, et al.
Published: (2025-01-01)

Protocol of DEXPED trial: efficacy of intravenous dexamethasone, administered at the time of analgesic blocking of the lower limb, on postoperative pain in children: a randomised, placebo-controlled, double-blind trial
by: Nathalie Thilly, et al.
Published: (2020-09-01)

Cadaveric simulation versus standard training for postgraduate trauma and orthopaedic surgical trainees: protocol for the CAD:TRAUMA study multicentre randomised controlled educational trial
by: Damian Griffin, et al.
Published: (2020-09-01)

Aluminium adjuvants versus placebo or no intervention in vaccine randomised clinical trials: a systematic review with meta-analysis and Trial Sequential Analysis
by: Christian Gluud, et al.
Published: (2022-06-01)

Health checks for autistic adults: study protocol for a cluster randomised controlled trial
by: Jeremy R. Parr, et al.
Published: (2024-12-01)

Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapy (PPOIT) in inducing desensitisation or tolerance in children with peanut allergy compared with oral immunotherapy (OIT) alone and with placebo (the PPOIT-003 study)
by: Michael O’Sullivan, et al.
Published: (2020-09-01)

Value of ctDNA in surveillance of adjuvant chemosensitivity and regimen adjustment in stage III colon cancer: a protocol for phase II multicentre randomised controlled trial (REVISE trial)
by: Jun Huang, et al.
Published: (2025-01-01)

Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease
by: Jeremy Chataway, et al.
Published: (2022-07-01)

Augmenting neurocognitive remediation therapy to Preventive Cognitive Therapy for partially remitted depressed patients: protocol of a pragmatic multicentre randomised controlled trial
by: Huibert Burger, et al.
Published: (2022-06-01)

Clinical and cost-effectiveness of Knee Arthroplasty versus Joint Distraction for Osteoarthritis (KARDS): protocol for a multicentre, phase III, randomised control trial
by: Deborah D Stocken, et al.
Published: (2022-06-01)