Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer

Abstract Background Whether localized surgical treatment has advantages over traditional hormone therapy for young women who desire to preserve their fertility and have Stage 1a and Grade 1 endometrial cancer. Case presentation We present a case study of a patient who was diagnosed with endometrial...

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Main Authors: Qianhua Xu, Hedong Lu, Xiaolei Wang, Min Li, Weiwei Zou
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-01750-w
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author Qianhua Xu
Hedong Lu
Xiaolei Wang
Min Li
Weiwei Zou
author_facet Qianhua Xu
Hedong Lu
Xiaolei Wang
Min Li
Weiwei Zou
author_sort Qianhua Xu
collection DOAJ
description Abstract Background Whether localized surgical treatment has advantages over traditional hormone therapy for young women who desire to preserve their fertility and have Stage 1a and Grade 1 endometrial cancer. Case presentation We present a case study of a patient who was diagnosed with endometrial cancer (Grade 1a, Stage 1) and was experiencing infertility. The patient underwent conservative surgical treatment and was able to successfully conceive through in vitro fertilization (IVF). She delivered a healthy male child. The treatment involved hysteroscopic excision of the lesion followed by three cycles of transplantation. In the third cycle, endometrial preparation was done through HMG injection. On the 24th day of transplantation, an ultrasound was performed which indicated an intrauterine pregnancy. The patient received routine obstetric care and delivered a male baby via cesarean section at 38 weeks of gestation. The baby had an Apgar score of 10. (After delivery, follow up for a check-up). Conclusions Conservative surgical treatment of Stage 1a and Grade 1 endometrial cancer can reduce the treatment duration compared to conventional hormonal therapy. This indicates that conservative surgical treatment of early-stage endometrial cancer followed by in-vitro fertilization (IVF) is a feasible alternative for young women who desire to preserve their fertility.
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publisher Springer
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series Discover Oncology
spelling doaj-art-2223786f92a6405daf8f7befe5cbde5a2025-01-12T12:29:11ZengSpringerDiscover Oncology2730-60112025-01-011611610.1007/s12672-025-01750-wSurgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancerQianhua Xu0Hedong Lu1Xiaolei Wang2Min Li3Weiwei Zou4Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical UniversityReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical UniversityReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical UniversityReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical UniversityReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical UniversityAbstract Background Whether localized surgical treatment has advantages over traditional hormone therapy for young women who desire to preserve their fertility and have Stage 1a and Grade 1 endometrial cancer. Case presentation We present a case study of a patient who was diagnosed with endometrial cancer (Grade 1a, Stage 1) and was experiencing infertility. The patient underwent conservative surgical treatment and was able to successfully conceive through in vitro fertilization (IVF). She delivered a healthy male child. The treatment involved hysteroscopic excision of the lesion followed by three cycles of transplantation. In the third cycle, endometrial preparation was done through HMG injection. On the 24th day of transplantation, an ultrasound was performed which indicated an intrauterine pregnancy. The patient received routine obstetric care and delivered a male baby via cesarean section at 38 weeks of gestation. The baby had an Apgar score of 10. (After delivery, follow up for a check-up). Conclusions Conservative surgical treatment of Stage 1a and Grade 1 endometrial cancer can reduce the treatment duration compared to conventional hormonal therapy. This indicates that conservative surgical treatment of early-stage endometrial cancer followed by in-vitro fertilization (IVF) is a feasible alternative for young women who desire to preserve their fertility.https://doi.org/10.1007/s12672-025-01750-wLocalized surgical treatmentIVFEndometrial cancerPregnancy
spellingShingle Qianhua Xu
Hedong Lu
Xiaolei Wang
Min Li
Weiwei Zou
Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
Discover Oncology
Localized surgical treatment
IVF
Endometrial cancer
Pregnancy
title Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
title_full Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
title_fullStr Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
title_full_unstemmed Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
title_short Surgical treatment can provide the opportunity for in-vitro fertilization (IVF) in a shorter period of time for patients with early-stage endometrial cancer
title_sort surgical treatment can provide the opportunity for in vitro fertilization ivf in a shorter period of time for patients with early stage endometrial cancer
topic Localized surgical treatment
IVF
Endometrial cancer
Pregnancy
url https://doi.org/10.1007/s12672-025-01750-w
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AT xiaoleiwang surgicaltreatmentcanprovidetheopportunityforinvitrofertilizationivfinashorterperiodoftimeforpatientswithearlystageendometrialcancer
AT minli surgicaltreatmentcanprovidetheopportunityforinvitrofertilizationivfinashorterperiodoftimeforpatientswithearlystageendometrialcancer
AT weiweizou surgicaltreatmentcanprovidetheopportunityforinvitrofertilizationivfinashorterperiodoftimeforpatientswithearlystageendometrialcancer