Functionalized graphene MOFs in drug delivery application

The research of the MOFs for biological activities have garnered a lot of interest in current history. Because of their exceptionally wide surfaces, and permeability, Metal-organic framework are thought to be an exciting type of nanocarriers for the dlivery of pharmaceuticals. The unique characteris...

Full description

Saved in:
Bibliographic Details
Main Authors: Chopra Lalita, Arul Prishya A.S., Manikanika, Bose Diotima, Chauhan Ashish Singh, Alhadrawi Merwa, Singh Karanpal, Sharma Rahul
Format: Article
Language:English
Published: EDP Sciences 2024-01-01
Series:E3S Web of Conferences
Subjects:
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/118/e3sconf_sne2-2024_02016.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846161136912695296
author Chopra Lalita
Arul Prishya A.S.
Manikanika
Bose Diotima
Chauhan Ashish Singh
Alhadrawi Merwa
Singh Karanpal
Sharma Rahul
author_facet Chopra Lalita
Arul Prishya A.S.
Manikanika
Bose Diotima
Chauhan Ashish Singh
Alhadrawi Merwa
Singh Karanpal
Sharma Rahul
author_sort Chopra Lalita
collection DOAJ
description The research of the MOFs for biological activities have garnered a lot of interest in current history. Because of their exceptionally wide surfaces, and permeability, Metal-organic framework are thought to be an exciting type of nanocarriers for the dlivery of pharmaceuticals. The unique characteristics of MOFs and their advantages as Nanomaterials for drug administration in therapeutic systemshave been reviewed in the first half of this paper. The most current techniques included hydrophilic group, pore encapsulated, covatent linkin, and using basic components of useful molecules. Strong bonds are used to join inorganic and organic units to create according to the utilization of metal-organic frameworks versality of the elements, structure, dimension, and usefulness, more that twenty thousdand different MOFs have been reported and investigated in the last ten years. An overview, different types of ligands, and numerous techniques for MOF synthesis are given at the beginning of the chapter. In many applications where MOFs are potential options, the special property of MOFs has been a significant problem. The latest scientific applications of MOFs for aptamer- specific intracellular drug, protein, and nucleic acid delivery were discussed. Finally, issues and opportunities were thoroughly covered to set the stage for the evolution of MOFs into an effective drug delivery system in the future.
format Article
id doaj-art-21efa3a8229d4be79a6a6117c5580abd
institution Kabale University
issn 2267-1242
language English
publishDate 2024-01-01
publisher EDP Sciences
record_format Article
series E3S Web of Conferences
spelling doaj-art-21efa3a8229d4be79a6a6117c5580abd2024-11-21T11:28:20ZengEDP SciencesE3S Web of Conferences2267-12422024-01-015880201610.1051/e3sconf/202458802016e3sconf_sne2-2024_02016Functionalized graphene MOFs in drug delivery applicationChopra Lalita0Arul Prishya A.S.1Manikanika2Bose Diotima3Chauhan Ashish Singh4Alhadrawi Merwa5Singh Karanpal6Sharma Rahul7Department of Chemistry, UIS, Chandigarh UniversityChemistry Department, University of New HampshireDepartment of Chemistry, UIS, Chandigarh UniversityChemistry Department, University of New HampshireUttaranchal Institute of Pharmaceutical Sciences, Division of Research and Innovation, Uttaranchal UniversityDepartment of Refrigeration and Air Conditioning Techniques, College of Technical Engineering, The Islamic UniversityResearch & Incubation Centre, Rayat Bahra UniversitySchool of Pharmaceutical Sciences, Bahra UniversityThe research of the MOFs for biological activities have garnered a lot of interest in current history. Because of their exceptionally wide surfaces, and permeability, Metal-organic framework are thought to be an exciting type of nanocarriers for the dlivery of pharmaceuticals. The unique characteristics of MOFs and their advantages as Nanomaterials for drug administration in therapeutic systemshave been reviewed in the first half of this paper. The most current techniques included hydrophilic group, pore encapsulated, covatent linkin, and using basic components of useful molecules. Strong bonds are used to join inorganic and organic units to create according to the utilization of metal-organic frameworks versality of the elements, structure, dimension, and usefulness, more that twenty thousdand different MOFs have been reported and investigated in the last ten years. An overview, different types of ligands, and numerous techniques for MOF synthesis are given at the beginning of the chapter. In many applications where MOFs are potential options, the special property of MOFs has been a significant problem. The latest scientific applications of MOFs for aptamer- specific intracellular drug, protein, and nucleic acid delivery were discussed. Finally, issues and opportunities were thoroughly covered to set the stage for the evolution of MOFs into an effective drug delivery system in the future.https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/118/e3sconf_sne2-2024_02016.pdfmetal-organic frameworksbiomoleculesdrug deliverystimulus-responsivenanocarriersgraphenebiomedical
spellingShingle Chopra Lalita
Arul Prishya A.S.
Manikanika
Bose Diotima
Chauhan Ashish Singh
Alhadrawi Merwa
Singh Karanpal
Sharma Rahul
Functionalized graphene MOFs in drug delivery application
E3S Web of Conferences
metal-organic frameworks
biomolecules
drug delivery
stimulus-responsive
nanocarriers
graphene
biomedical
title Functionalized graphene MOFs in drug delivery application
title_full Functionalized graphene MOFs in drug delivery application
title_fullStr Functionalized graphene MOFs in drug delivery application
title_full_unstemmed Functionalized graphene MOFs in drug delivery application
title_short Functionalized graphene MOFs in drug delivery application
title_sort functionalized graphene mofs in drug delivery application
topic metal-organic frameworks
biomolecules
drug delivery
stimulus-responsive
nanocarriers
graphene
biomedical
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/118/e3sconf_sne2-2024_02016.pdf
work_keys_str_mv AT chopralalita functionalizedgraphenemofsindrugdeliveryapplication
AT arulprishyaas functionalizedgraphenemofsindrugdeliveryapplication
AT manikanika functionalizedgraphenemofsindrugdeliveryapplication
AT bosediotima functionalizedgraphenemofsindrugdeliveryapplication
AT chauhanashishsingh functionalizedgraphenemofsindrugdeliveryapplication
AT alhadrawimerwa functionalizedgraphenemofsindrugdeliveryapplication
AT singhkaranpal functionalizedgraphenemofsindrugdeliveryapplication
AT sharmarahul functionalizedgraphenemofsindrugdeliveryapplication