Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases

Objective:To observe the curative effect of repetitive transcranial magnetic stimulation (rTMS) combined with fluoxetine in treatment of post-stroke depression (PSD) with stagnation of liver-Qi syndrome.Methods:Sixty-six PSD patients were assigned to treatment group and control group by the random n...

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Main Authors: Cheng LI, Xiaoai LI, Hui LIANG, Nianwen YAN, Yanxu WANG
Format: Article
Language:English
Published: Editorial Office of Rehabilitation Medicine 2016-12-01
Series:康复学报
Subjects:
Online Access:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2016.06014
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author Cheng LI
Xiaoai LI
Hui LIANG
Nianwen YAN
Yanxu WANG
author_facet Cheng LI
Xiaoai LI
Hui LIANG
Nianwen YAN
Yanxu WANG
author_sort Cheng LI
collection DOAJ
description Objective:To observe the curative effect of repetitive transcranial magnetic stimulation (rTMS) combined with fluoxetine in treatment of post-stroke depression (PSD) with stagnation of liver-Qi syndrome.Methods:Sixty-six PSD patients were assigned to treatment group and control group by the random number table, and 33 patients in each group. Both of two groups received fluoxetine, once every morning; and the treatment group was added with rTMS, once a day. The treatment lasted for two weeks. The national institute of health stroke scale (NIHSS), Hamilton depression (HAMD) scale, TCM syndrome score of liver-Qi stagnation and treatment emergent symptom scale (TESS) were used to evaluate the curative effect of two groups.Results:After the treatment, the NIHSS, HAMD and TCM syndrome score were decreased in both groups (<italic>P</italic>&lt;0.05), and the decreasing amplitude in the treatment group was higher than that in the control group, and there was a significant difference between them (<italic>P</italic>&lt;0.05). After the treatment, there were significant differences in the improvement of depressive symptoms and TCM syndrome score between the two groups, and the curative effect of treatment group was better than that of the control group (<italic>P</italic>&lt;0.05). There was a significant difference in the incidence of adverse reactions between the two groups, and the incidence in the treatment group was less than that in the control group (<italic>P</italic>&lt;0.05).Conclusion:rTMS could improve PSD and TCM syndrome and attenuate neurological deficits, as well as rTMS could reduce adverse reactions of fluoxetine and increase the patient's compliance.
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spelling doaj-art-21ef1b8fa22744bdb2aab5502e22a8762025-01-14T10:05:58ZengEditorial Office of Rehabilitation Medicine康复学报2096-03282016-12-01261418,2323096600Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 CasesCheng LIXiaoai LIHui LIANGNianwen YANYanxu WANGObjective:To observe the curative effect of repetitive transcranial magnetic stimulation (rTMS) combined with fluoxetine in treatment of post-stroke depression (PSD) with stagnation of liver-Qi syndrome.Methods:Sixty-six PSD patients were assigned to treatment group and control group by the random number table, and 33 patients in each group. Both of two groups received fluoxetine, once every morning; and the treatment group was added with rTMS, once a day. The treatment lasted for two weeks. The national institute of health stroke scale (NIHSS), Hamilton depression (HAMD) scale, TCM syndrome score of liver-Qi stagnation and treatment emergent symptom scale (TESS) were used to evaluate the curative effect of two groups.Results:After the treatment, the NIHSS, HAMD and TCM syndrome score were decreased in both groups (<italic>P</italic>&lt;0.05), and the decreasing amplitude in the treatment group was higher than that in the control group, and there was a significant difference between them (<italic>P</italic>&lt;0.05). After the treatment, there were significant differences in the improvement of depressive symptoms and TCM syndrome score between the two groups, and the curative effect of treatment group was better than that of the control group (<italic>P</italic>&lt;0.05). There was a significant difference in the incidence of adverse reactions between the two groups, and the incidence in the treatment group was less than that in the control group (<italic>P</italic>&lt;0.05).Conclusion:rTMS could improve PSD and TCM syndrome and attenuate neurological deficits, as well as rTMS could reduce adverse reactions of fluoxetine and increase the patient's compliance.http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2016.06014repetitive transcranial magnetic stimulationpost-stroke depressionstagnation of liver-QiTCM syndrome score
spellingShingle Cheng LI
Xiaoai LI
Hui LIANG
Nianwen YAN
Yanxu WANG
Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases
康复学报
repetitive transcranial magnetic stimulation
post-stroke depression
stagnation of liver-Qi
TCM syndrome score
title Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases
title_full Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases
title_fullStr Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases
title_full_unstemmed Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases
title_short Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases
title_sort repetitive transcranial magnetic stimulation for treatment of post stroke depression of liver qi stagnation type in 33 cases
topic repetitive transcranial magnetic stimulation
post-stroke depression
stagnation of liver-Qi
TCM syndrome score
url http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2016.06014
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