Repetitive Transcranial Magnetic Stimulation for Treatment of Post-stroke Depression of Liver-Qi Stagnation Type in 33 Cases
Objective:To observe the curative effect of repetitive transcranial magnetic stimulation (rTMS) combined with fluoxetine in treatment of post-stroke depression (PSD) with stagnation of liver-Qi syndrome.Methods:Sixty-six PSD patients were assigned to treatment group and control group by the random n...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Office of Rehabilitation Medicine
2016-12-01
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| Series: | 康复学报 |
| Subjects: | |
| Online Access: | http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2016.06014 |
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| Summary: | Objective:To observe the curative effect of repetitive transcranial magnetic stimulation (rTMS) combined with fluoxetine in treatment of post-stroke depression (PSD) with stagnation of liver-Qi syndrome.Methods:Sixty-six PSD patients were assigned to treatment group and control group by the random number table, and 33 patients in each group. Both of two groups received fluoxetine, once every morning; and the treatment group was added with rTMS, once a day. The treatment lasted for two weeks. The national institute of health stroke scale (NIHSS), Hamilton depression (HAMD) scale, TCM syndrome score of liver-Qi stagnation and treatment emergent symptom scale (TESS) were used to evaluate the curative effect of two groups.Results:After the treatment, the NIHSS, HAMD and TCM syndrome score were decreased in both groups (<italic>P</italic><0.05), and the decreasing amplitude in the treatment group was higher than that in the control group, and there was a significant difference between them (<italic>P</italic><0.05). After the treatment, there were significant differences in the improvement of depressive symptoms and TCM syndrome score between the two groups, and the curative effect of treatment group was better than that of the control group (<italic>P</italic><0.05). There was a significant difference in the incidence of adverse reactions between the two groups, and the incidence in the treatment group was less than that in the control group (<italic>P</italic><0.05).Conclusion:rTMS could improve PSD and TCM syndrome and attenuate neurological deficits, as well as rTMS could reduce adverse reactions of fluoxetine and increase the patient's compliance. |
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| ISSN: | 2096-0328 |