Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database
Background: Heart Failure (HF) and Diabetes Mellitus (DM) often coexist, and each condition independently increases the likelihood of developing the other. While there has been concern regarding the increasing burden of disease for both conditions individually over the last decade, a comprehensive e...
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Elsevier
2024-12-01
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| Series: | International Journal of Cardiology. Cardiovascular Risk and Prevention |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772487524000916 |
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| author | Humza Saeed M.B.B.S. Abdullah Irum Naeem Amna Zafar Bilal Ahmad Taimur ul Islam Syed Saaid Rizvi Nikita Kumari Syed Ghazi Ali Kirmani Fatima Mansoor Amir Hassan Adarsh Raja Mohamed Daoud Aman Goyal |
| author_facet | Humza Saeed M.B.B.S. Abdullah Irum Naeem Amna Zafar Bilal Ahmad Taimur ul Islam Syed Saaid Rizvi Nikita Kumari Syed Ghazi Ali Kirmani Fatima Mansoor Amir Hassan Adarsh Raja Mohamed Daoud Aman Goyal |
| author_sort | Humza Saeed |
| collection | DOAJ |
| description | Background: Heart Failure (HF) and Diabetes Mellitus (DM) often coexist, and each condition independently increases the likelihood of developing the other. While there has been concern regarding the increasing burden of disease for both conditions individually over the last decade, a comprehensive examination of mortality trends and demographic and regional disparities needs to be thoroughly explored in the United States (US). Methods: This study analyzed death certificates from the CDC WONDER database, focusing on mortality caused by the co-occurrence of HF and DM in adults aged 75 and older from 1999 to 2020. Age-adjusted mortality rates (AAMRs) and annual percent changes (APCs) were computed and categorized by year, gender, race, census region, state, and metropolitan status. Results: A total of 663,016 deaths were reported in patients with coexisting HF and DM. Overall, AAMR increased from 154.1 to 186.1 per 100,000 population between 1999 and 2020, with a notable significant increase from 2018 to 2020 (APC: 11.30). Older men had consistently higher AAMRs than older women (185 vs. 135.4). Furthermore, we found that AAMRs were highest among non-Hispanic (NH) American Indian or Alaskan natives and lowest in NH Asian or Pacific Islanders (214.4 vs. 104.1). Similarly, AAMRs were highest in the Midwestern region and among those dwelling in non-metropolitan areas. Conclusions: Mortality from HF and DM has risen significantly in recent years, especially among older men, NH American Indian or Alaska Natives, and those in non-metropolitan areas. Urgent policies need to be developed to address these disparities and promote equitable healthcare access. |
| format | Article |
| id | doaj-art-21cd6aa9727b43e4b95c14fcc4de9188 |
| institution | Kabale University |
| issn | 2772-4875 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology. Cardiovascular Risk and Prevention |
| spelling | doaj-art-21cd6aa9727b43e4b95c14fcc4de91882024-11-28T04:35:20ZengElsevierInternational Journal of Cardiology. Cardiovascular Risk and Prevention2772-48752024-12-0123200326Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER databaseHumza Saeed0M.B.B.S. Abdullah1Irum Naeem2Amna Zafar3Bilal Ahmad4Taimur ul Islam5Syed Saaid Rizvi6Nikita Kumari7Syed Ghazi Ali Kirmani8Fatima Mansoor9Amir Hassan10Adarsh Raja11Mohamed Daoud12Aman Goyal13Rawalpindi Medical University, Rawalpindi, Punjab, PakistanRawalpindi Medical University, Rawalpindi, Punjab, PakistanKing Edward Medical University, Lahore, Punjab, PakistanKing Edward Medical University, Lahore, Punjab, PakistanDG Khan Medical College, Dera Ghazi Khan, Punjab, PakistanShifa college of medicine, Shifa Tameer e Millat University, Islamabad, PakistanSindh Medical College, Jinnah Sindh Medical University, Karachi, PakistanSindh Medical College, Jinnah Sindh Medical University, Karachi, PakistanAllama Iqbal Medical College, Lahore, Punjab, PakistanKarachi Medical and Dental College, Karachi, PakistanBronglais General Hospital, Aberystwyth, UKDepartment of Internal Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanBogomolets Medical University, Kyiv, Ukraine; Corresponding author. Bogomolets Medical University, Kyiv, UK.Department of Internal Medicine, Seth GS Medical College and KEM Hospital, Mumbai, IndiaBackground: Heart Failure (HF) and Diabetes Mellitus (DM) often coexist, and each condition independently increases the likelihood of developing the other. While there has been concern regarding the increasing burden of disease for both conditions individually over the last decade, a comprehensive examination of mortality trends and demographic and regional disparities needs to be thoroughly explored in the United States (US). Methods: This study analyzed death certificates from the CDC WONDER database, focusing on mortality caused by the co-occurrence of HF and DM in adults aged 75 and older from 1999 to 2020. Age-adjusted mortality rates (AAMRs) and annual percent changes (APCs) were computed and categorized by year, gender, race, census region, state, and metropolitan status. Results: A total of 663,016 deaths were reported in patients with coexisting HF and DM. Overall, AAMR increased from 154.1 to 186.1 per 100,000 population between 1999 and 2020, with a notable significant increase from 2018 to 2020 (APC: 11.30). Older men had consistently higher AAMRs than older women (185 vs. 135.4). Furthermore, we found that AAMRs were highest among non-Hispanic (NH) American Indian or Alaskan natives and lowest in NH Asian or Pacific Islanders (214.4 vs. 104.1). Similarly, AAMRs were highest in the Midwestern region and among those dwelling in non-metropolitan areas. Conclusions: Mortality from HF and DM has risen significantly in recent years, especially among older men, NH American Indian or Alaska Natives, and those in non-metropolitan areas. Urgent policies need to be developed to address these disparities and promote equitable healthcare access.http://www.sciencedirect.com/science/article/pii/S2772487524000916CoexistenceCOVID-19DiabetesHeart failureMortalityOlder adults |
| spellingShingle | Humza Saeed M.B.B.S. Abdullah Irum Naeem Amna Zafar Bilal Ahmad Taimur ul Islam Syed Saaid Rizvi Nikita Kumari Syed Ghazi Ali Kirmani Fatima Mansoor Amir Hassan Adarsh Raja Mohamed Daoud Aman Goyal Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database International Journal of Cardiology. Cardiovascular Risk and Prevention Coexistence COVID-19 Diabetes Heart failure Mortality Older adults |
| title | Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database |
| title_full | Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database |
| title_fullStr | Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database |
| title_full_unstemmed | Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database |
| title_short | Demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the United States between 1999 and 2020: A retrospective population-based cohort study from the CDC WONDER database |
| title_sort | demographic trends and disparities in mortality related to coexisting heart failure and diabetes mellitus among older adults in the united states between 1999 and 2020 a retrospective population based cohort study from the cdc wonder database |
| topic | Coexistence COVID-19 Diabetes Heart failure Mortality Older adults |
| url | http://www.sciencedirect.com/science/article/pii/S2772487524000916 |
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