A smartphone application as a promising tool for large-scale collection of participant data on fertility treatment
Abstract In Japan, there is a registry for fertility treatment (the JSOG registry), which is a system that only registers select clinical data related to assisted reproductive technology (ART). This system does not include patient-derived data, so innovative tools that can complement the shortcoming...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-08043-w |
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| author | Ryo Yokomizo Tsuguhiko Kato Kevin Y. Urayama Akari Nakamura Makoto Sato Risa Nasu Maaya Hine Hiroshi Kishi Haruhiko Sago Aikou Okamoto Akihiro Umezawa |
| author_facet | Ryo Yokomizo Tsuguhiko Kato Kevin Y. Urayama Akari Nakamura Makoto Sato Risa Nasu Maaya Hine Hiroshi Kishi Haruhiko Sago Aikou Okamoto Akihiro Umezawa |
| author_sort | Ryo Yokomizo |
| collection | DOAJ |
| description | Abstract In Japan, there is a registry for fertility treatment (the JSOG registry), which is a system that only registers select clinical data related to assisted reproductive technology (ART). This system does not include patient-derived data, so innovative tools that can complement the shortcomings of the existing registry may be useful. In this study we explored the potential of using a smartphone application platform to collect clinical data from patients directly. We recruited participants using the smartphone application “Luna Luna” and requested information that is typically gathered during a medical checkup, including basic physical characteristics, medical history, and results of fertility examinations such as hormone levels and semen analysis. We also asked the participants about the most recent fertility treatment they received and the details of the treatment. We recruited more than 13,000 participants within Japan nationwide in one month, and successfully collected information that is necessary in clinical practice for fertility treatment. Furthermore, through the participants, we were able to obtain information concerning their partners. We gained an expanded understanding of the circumstances surrounding fertility tests performed in Japan and details of fertility treatment such as ovarian stimulation and pregnancy outcomes by each fertility treatment method. This smartphone application has the potential as a promising tool for doctors and couples for information management during fertility treatment. |
| format | Article |
| id | doaj-art-21c2a62a46a749a5aa3b3f171c2c2022 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-21c2a62a46a749a5aa3b3f171c2c20222025-08-20T03:45:35ZengNature PortfolioScientific Reports2045-23222025-07-0115111110.1038/s41598-025-08043-wA smartphone application as a promising tool for large-scale collection of participant data on fertility treatmentRyo Yokomizo0Tsuguhiko Kato1Kevin Y. Urayama2Akari Nakamura3Makoto Sato4Risa Nasu5Maaya Hine6Hiroshi Kishi7Haruhiko Sago8Aikou Okamoto9Akihiro Umezawa10Center for Regenerative Medicine, National Center for Child Health and Development Research InstituteDepartment of Social Medicine, National Center for Child Health and DevelopmentDepartment of Social Medicine, National Center for Child Health and DevelopmentDepartment of Healthcare Business, MTI LtdDepartment of Healthcare Business, MTI LtdDepartment of Healthcare Business, MTI LtdDepartment of Healthcare Business, MTI LtdDepartment of Obstetrics and Gynecology, The Jikei University School of MedicineCenter for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and DevelopmentDepartment of Obstetrics and Gynecology, The Jikei University School of MedicineCenter for Regenerative Medicine, National Center for Child Health and Development Research InstituteAbstract In Japan, there is a registry for fertility treatment (the JSOG registry), which is a system that only registers select clinical data related to assisted reproductive technology (ART). This system does not include patient-derived data, so innovative tools that can complement the shortcomings of the existing registry may be useful. In this study we explored the potential of using a smartphone application platform to collect clinical data from patients directly. We recruited participants using the smartphone application “Luna Luna” and requested information that is typically gathered during a medical checkup, including basic physical characteristics, medical history, and results of fertility examinations such as hormone levels and semen analysis. We also asked the participants about the most recent fertility treatment they received and the details of the treatment. We recruited more than 13,000 participants within Japan nationwide in one month, and successfully collected information that is necessary in clinical practice for fertility treatment. Furthermore, through the participants, we were able to obtain information concerning their partners. We gained an expanded understanding of the circumstances surrounding fertility tests performed in Japan and details of fertility treatment such as ovarian stimulation and pregnancy outcomes by each fertility treatment method. This smartphone application has the potential as a promising tool for doctors and couples for information management during fertility treatment.https://doi.org/10.1038/s41598-025-08043-wSmartphone applicationFertility treatmentInfertilityReproductive medicineVirtual surveillance |
| spellingShingle | Ryo Yokomizo Tsuguhiko Kato Kevin Y. Urayama Akari Nakamura Makoto Sato Risa Nasu Maaya Hine Hiroshi Kishi Haruhiko Sago Aikou Okamoto Akihiro Umezawa A smartphone application as a promising tool for large-scale collection of participant data on fertility treatment Scientific Reports Smartphone application Fertility treatment Infertility Reproductive medicine Virtual surveillance |
| title | A smartphone application as a promising tool for large-scale collection of participant data on fertility treatment |
| title_full | A smartphone application as a promising tool for large-scale collection of participant data on fertility treatment |
| title_fullStr | A smartphone application as a promising tool for large-scale collection of participant data on fertility treatment |
| title_full_unstemmed | A smartphone application as a promising tool for large-scale collection of participant data on fertility treatment |
| title_short | A smartphone application as a promising tool for large-scale collection of participant data on fertility treatment |
| title_sort | smartphone application as a promising tool for large scale collection of participant data on fertility treatment |
| topic | Smartphone application Fertility treatment Infertility Reproductive medicine Virtual surveillance |
| url | https://doi.org/10.1038/s41598-025-08043-w |
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