The pathomechanism of bone marrow edema in the femoral head necrosis with pericollapse stage

The pathomechanism of bone marrow edema in the femoral head necrosis with pericollapse stage

Abstract Bone marrow edema (BME), a notable manifestation during the progression of osteonecrosis of the femoral head (ONFH), exhibits significant associations with femoral head collapse, pain, and prognosis, howeverits’ pathogenesis remains underexplored. In this study, specimens from patients unde...

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Bibliographic Details
Main Authors: Liang Mo, Zhangzheng Wang, Mengyu Jiang, Chi Zhou, Chao Ma, Yinuo Fan, Wei He, Zhenqiu Chen, Yuhao Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Osteonecrosis of the femoral head
Bone marrow edema
Osteoclast
Inflammation
Oxidative stress
Online Access:https://doi.org/10.1038/s41598-024-83376-6
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