Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics

Pesticide residues, resulting from agricultural practices, pose significant health and environmental risks. This review synthesizes the current understanding of pesticide impacts on the immune system, highlighting their role in chronic diseases such as asthma, diabetes, Parkinson's disease (PD)...

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Main Authors: Lingling Cao, Qiyuan Kang, Yuan Tian
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324014118
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author Lingling Cao
Qiyuan Kang
Yuan Tian
author_facet Lingling Cao
Qiyuan Kang
Yuan Tian
author_sort Lingling Cao
collection DOAJ
description Pesticide residues, resulting from agricultural practices, pose significant health and environmental risks. This review synthesizes the current understanding of pesticide impacts on the immune system, highlighting their role in chronic diseases such as asthma, diabetes, Parkinson's disease (PD) and cancer. We emphasize the significant role of omics technologies in the study of pesticide toxicity mechanisms. The integration of genomics, proteomics, metabolomics, and epigenomics offers a multidimensional strategy for a comprehensive assessment of pesticide effects, facilitating personalized risk management and policy formulation. We advocate for stringent regulatory policies, public education, and global cooperation to enhance food safety and environmental sustainability. By adopting a unified approach, we aim to mitigate the risks of pesticide residues, ensuring human health and ecological balance are preserved.
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institution Kabale University
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publishDate 2024-11-01
publisher Elsevier
record_format Article
series Ecotoxicology and Environmental Safety
spelling doaj-art-2169fd5ef7d4471b8dcf787fa63e7ce22024-11-21T06:02:14ZengElsevierEcotoxicology and Environmental Safety0147-65132024-11-01287117335Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omicsLingling Cao0Qiyuan Kang1Yuan Tian2Department of Pharmacology, Clinical School of Medicine, Changchun University of Chinese Medicine, Changchun, Jilin Province, ChinaChangchun University of Chinese Medicine, Changchun, Jilin Province, ChinaDepartment of Pathology and Pathophysiology, Clinical School of Medicine, Changchun University of Chinese Medicine, Changchun, Jilin Province, China; Corresponding author.Pesticide residues, resulting from agricultural practices, pose significant health and environmental risks. This review synthesizes the current understanding of pesticide impacts on the immune system, highlighting their role in chronic diseases such as asthma, diabetes, Parkinson's disease (PD) and cancer. We emphasize the significant role of omics technologies in the study of pesticide toxicity mechanisms. The integration of genomics, proteomics, metabolomics, and epigenomics offers a multidimensional strategy for a comprehensive assessment of pesticide effects, facilitating personalized risk management and policy formulation. We advocate for stringent regulatory policies, public education, and global cooperation to enhance food safety and environmental sustainability. By adopting a unified approach, we aim to mitigate the risks of pesticide residues, ensuring human health and ecological balance are preserved.http://www.sciencedirect.com/science/article/pii/S0147651324014118PesticidesImmune system impactChronic diseasesOmics technologiesFood safety
spellingShingle Lingling Cao
Qiyuan Kang
Yuan Tian
Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics
Ecotoxicology and Environmental Safety
Pesticides
Immune system impact
Chronic diseases
Omics technologies
Food safety
title Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics
title_full Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics
title_fullStr Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics
title_full_unstemmed Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics
title_short Pesticide residues: Bridging the gap between environmental exposure and chronic disease through omics
title_sort pesticide residues bridging the gap between environmental exposure and chronic disease through omics
topic Pesticides
Immune system impact
Chronic diseases
Omics technologies
Food safety
url http://www.sciencedirect.com/science/article/pii/S0147651324014118
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AT qiyuankang pesticideresiduesbridgingthegapbetweenenvironmentalexposureandchronicdiseasethroughomics
AT yuantian pesticideresiduesbridgingthegapbetweenenvironmentalexposureandchronicdiseasethroughomics