Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study
Abstract Cervical spondylotic myelopathy (CSM) is a neurological disorder characterized by degenerative changes in the spinal cord and compression of the spinal cord and its adjacent structures due to various reasons, such as intervertebral disc herniation. The Japan Orthopaedic Association score is...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-83429-w |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841559486472388608 |
|---|---|
| author | He Ling Gaoyong Deng Shaohuai Xia Wencai Li Rongbin Lu Mingjian Lin Zhao Huang |
| author_facet | He Ling Gaoyong Deng Shaohuai Xia Wencai Li Rongbin Lu Mingjian Lin Zhao Huang |
| author_sort | He Ling |
| collection | DOAJ |
| description | Abstract Cervical spondylotic myelopathy (CSM) is a neurological disorder characterized by degenerative changes in the spinal cord and compression of the spinal cord and its adjacent structures due to various reasons, such as intervertebral disc herniation. The Japan Orthopaedic Association score is a disease-specific outcome tool that provides quantitative measurements for CSM patients. At present, no scholars have developed a model that can directly predict the prognosis of CSM patients. This study used binary logistic regression analysis to identify clinical independent predictive factors, and then used R language to construct a nomogram. The results showed that Hb (0.71 [0.51, 0.99]), LYM (0.32 [0.22, 0.46]), and ALB (0.32 [0.23, 0.45]) were independent predictive factors. Good prediction performance with modest errors was shown by the nomogram in both the training and validation groups. Hb, LYM, ALB are independent predictors of the prognosis of ACDF in CSM patients. The constructed nomogram can help clinicians assess and treat patients early, benefiting more patients. |
| format | Article |
| id | doaj-art-214c1e02862c4f409e52fb717fb0f5f1 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-214c1e02862c4f409e52fb717fb0f5f12025-01-05T12:26:46ZengNature PortfolioScientific Reports2045-23222024-12-0114111210.1038/s41598-024-83429-wConstruction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective studyHe Ling0Gaoyong Deng1Shaohuai Xia2Wencai Li3Rongbin Lu4Mingjian Lin5Zhao Huang6Department of Orthopedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Spine Surgery, The Affiliated Hospital of Guilin Medical UniversityDepartment of Neurotumor, Beijing Xiaotangshan HospitalDepartment of Orthopedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Orthopedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical UniversityDepartment of Neurosurgery, Gaozhou People’s HospitalDepartment of Orthopedics Trauma and Hand Surgery, The First Affiliated Hospital of Guangxi Medical UniversityAbstract Cervical spondylotic myelopathy (CSM) is a neurological disorder characterized by degenerative changes in the spinal cord and compression of the spinal cord and its adjacent structures due to various reasons, such as intervertebral disc herniation. The Japan Orthopaedic Association score is a disease-specific outcome tool that provides quantitative measurements for CSM patients. At present, no scholars have developed a model that can directly predict the prognosis of CSM patients. This study used binary logistic regression analysis to identify clinical independent predictive factors, and then used R language to construct a nomogram. The results showed that Hb (0.71 [0.51, 0.99]), LYM (0.32 [0.22, 0.46]), and ALB (0.32 [0.23, 0.45]) were independent predictive factors. Good prediction performance with modest errors was shown by the nomogram in both the training and validation groups. Hb, LYM, ALB are independent predictors of the prognosis of ACDF in CSM patients. The constructed nomogram can help clinicians assess and treat patients early, benefiting more patients.https://doi.org/10.1038/s41598-024-83429-wCervical spondylotic myelopathyAnterior cervical discectomy and fusionPrognosisNomogram |
| spellingShingle | He Ling Gaoyong Deng Shaohuai Xia Wencai Li Rongbin Lu Mingjian Lin Zhao Huang Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study Scientific Reports Cervical spondylotic myelopathy Anterior cervical discectomy and fusion Prognosis Nomogram |
| title | Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study |
| title_full | Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study |
| title_fullStr | Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study |
| title_full_unstemmed | Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study |
| title_short | Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study |
| title_sort | construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy a retrospective study |
| topic | Cervical spondylotic myelopathy Anterior cervical discectomy and fusion Prognosis Nomogram |
| url | https://doi.org/10.1038/s41598-024-83429-w |
| work_keys_str_mv | AT heling constructionofanomogramforpredictingtheprognosisofpatientswithcervicalspondyloticmyelopathyaretrospectivestudy AT gaoyongdeng constructionofanomogramforpredictingtheprognosisofpatientswithcervicalspondyloticmyelopathyaretrospectivestudy AT shaohuaixia constructionofanomogramforpredictingtheprognosisofpatientswithcervicalspondyloticmyelopathyaretrospectivestudy AT wencaili constructionofanomogramforpredictingtheprognosisofpatientswithcervicalspondyloticmyelopathyaretrospectivestudy AT rongbinlu constructionofanomogramforpredictingtheprognosisofpatientswithcervicalspondyloticmyelopathyaretrospectivestudy AT mingjianlin constructionofanomogramforpredictingtheprognosisofpatientswithcervicalspondyloticmyelopathyaretrospectivestudy AT zhaohuang constructionofanomogramforpredictingtheprognosisofpatientswithcervicalspondyloticmyelopathyaretrospectivestudy |