LYMPHOPENIA AS A FACTOR INVOLVED IN THE AUTOIMMUNITY DEVELOPMENT IN MURINE GRAFT VS. HOST DISEASE

Syngeneic splenocyte transplantation leads to lymphopenia development in intact mice owing to decreased proliferative activity of bone marrow hematopoietic progenitor cells. In the mice with induced chronic graft-versus-host disease (cGVHD) transfer of syngeneic lymphocytes has little or no effect o...

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Bibliographic Details
Main Authors: E. V. Goiman, V. O. Tkachev, O. T. Kudayeva, O. P. Kolesnikova, V. A. Kozlov
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2012-05-01
Series:Acta Biomedica Scientifica
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Online Access:https://www.actabiomedica.ru/jour/article/view/932
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