High-precision neural information detection of multiple brain regions in mice under different concentrations of isoflurane anesthesia based on microelectrode arrays

Abstract The precise neural mechanisms by which general anesthetics induce unconsciousness remain undetermined, with ongoing debate over whether they primarily affect the cortex directly or act predominantly on the sleep–wake brain regions. There is an urgent need for high-precision methodologies to...

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Bibliographic Details
Main Authors: Yiming Duan, Qianli Jia, Jinping Luo, Yu Wang, Qi Li, Shiya Lv, Luyi Jing, Wei Xu, Xiaoying Zhang, Yulong Ma, Weidong Mi, Xinxia Cai
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-025-00944-0
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