Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantation

ObjectiveTo explore the effect of Jinhoujian spray on postoperative sore throat (POST) after implantation of streamlined liner of pharyngeal airway (SLIPA) in general anesthesia. MethodsA total of 100 patients undergoing lower limb fracture surgery with laryngeal mask general anesthesia in Xuchang C...

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Main Authors: Lei WU, Yuanhua ZHENG, Ningzhe KANG, Yimeng XIA
Format: Article
Language:English
Published: Shanghai Chinese Clinical Medicine Press Co., Ltd. 2024-12-01
Series:Zhongguo Linchuang Yixue
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Online Access:https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2024.20241126
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author Lei WU
Yuanhua ZHENG
Ningzhe KANG
Yimeng XIA
author_facet Lei WU
Yuanhua ZHENG
Ningzhe KANG
Yimeng XIA
author_sort Lei WU
collection DOAJ
description ObjectiveTo explore the effect of Jinhoujian spray on postoperative sore throat (POST) after implantation of streamlined liner of pharyngeal airway (SLIPA) in general anesthesia. MethodsA total of 100 patients undergoing lower limb fracture surgery with laryngeal mask general anesthesia in Xuchang Central Hospital, Henan University of Science and Technology from January 1, 2024, to May 31, 2024 were randomly divided into Jinhoujian spray group (Jinhoujian group) and lidocaine aerosol group (lidocaine group), with 50 cases in each group. Jinhoujian spray and lidocaine aerosol were applied to both sides of the laryngeal mask sealing cover, and after intravenous induction of general anesthesia, the same anesthesiologist inserted the laryngeal mask using a blind probing standard method. Mean arterial pressure (MAP) and heart rate (HR) were compared between the two groups at different time points: before laryngeal mask insertion (T0), immediately after insertion (T1), 3 minutes after insertion (T2), 5 minutes after insertion (T3), 10 minutes after insertion (T4), immediately after mask removal (T5), 3 minutes after removal (T6), and 5 minutes after removal (T7). The incidences of stress responses (coughing, airway spasm, agitation, nausea and vomiting) and adverse reactions (tongue numbness, arytenoid joint dislocation, dysphagia, restricted protective reflexes, and pharyngeal arch injury) after laryngeal mask removal were compared between the two groups. The numeric rating scale (NRS) at 0.5 h, and NRS, hoarseness, and extubation reaction at 24 h after mask removal were compared between the two groups. ResultsThere were no statistically significant differences in baseline data and MAP and HR values at each time point (T0-7) between the two groups. Compared with the lidocaine group, the patients in Jinhoujian group had a lower incidence of nausea and vomiting after laryngeal mask removal (P=0.021). There was no statistically significant difference in the numeric rating scale (NRS) score 0.5 h after laryngeal mask removal between the two groups. Compared to the lidocaine group, the patients in Jinhoujian group had significantly lower scores of NRS (P=0.027), Prince-Henry (P=0.002), and oral mucositis (P=0.026) 24 h after laryngeal mask removal . ConclusionsJinhoujian spray can effectively reduce incidence of postoperative nausea and vomiting, alleviate POST and oral mucositis 24 h after laryngeal mask removal, improving patient comfort after lower limb fracture surgery.
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spelling doaj-art-20fbd95a4bb040c8b51a2b0d3259d6ab2024-12-26T02:58:50ZengShanghai Chinese Clinical Medicine Press Co., Ltd.Zhongguo Linchuang Yixue1008-63582024-12-0131688388810.12025/j.issn.1008-6358.2024.2024112620241126Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantationLei WU0Yuanhua ZHENG1Ningzhe KANG2Yimeng XIA3Department of Anesthesiology, Xuchang Central Hospital, Henan University of Science and Technology, Xuchang 461000, Henan, ChinaDepartment of Anesthesiology, Xuchang Central Hospital, Henan University of Science and Technology, Xuchang 461000, Henan, ChinaDepartment of Anesthesiology, Xuchang Central Hospital, Henan University of Science and Technology, Xuchang 461000, Henan, ChinaDepartment of Anesthesiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaObjectiveTo explore the effect of Jinhoujian spray on postoperative sore throat (POST) after implantation of streamlined liner of pharyngeal airway (SLIPA) in general anesthesia. MethodsA total of 100 patients undergoing lower limb fracture surgery with laryngeal mask general anesthesia in Xuchang Central Hospital, Henan University of Science and Technology from January 1, 2024, to May 31, 2024 were randomly divided into Jinhoujian spray group (Jinhoujian group) and lidocaine aerosol group (lidocaine group), with 50 cases in each group. Jinhoujian spray and lidocaine aerosol were applied to both sides of the laryngeal mask sealing cover, and after intravenous induction of general anesthesia, the same anesthesiologist inserted the laryngeal mask using a blind probing standard method. Mean arterial pressure (MAP) and heart rate (HR) were compared between the two groups at different time points: before laryngeal mask insertion (T0), immediately after insertion (T1), 3 minutes after insertion (T2), 5 minutes after insertion (T3), 10 minutes after insertion (T4), immediately after mask removal (T5), 3 minutes after removal (T6), and 5 minutes after removal (T7). The incidences of stress responses (coughing, airway spasm, agitation, nausea and vomiting) and adverse reactions (tongue numbness, arytenoid joint dislocation, dysphagia, restricted protective reflexes, and pharyngeal arch injury) after laryngeal mask removal were compared between the two groups. The numeric rating scale (NRS) at 0.5 h, and NRS, hoarseness, and extubation reaction at 24 h after mask removal were compared between the two groups. ResultsThere were no statistically significant differences in baseline data and MAP and HR values at each time point (T0-7) between the two groups. Compared with the lidocaine group, the patients in Jinhoujian group had a lower incidence of nausea and vomiting after laryngeal mask removal (P=0.021). There was no statistically significant difference in the numeric rating scale (NRS) score 0.5 h after laryngeal mask removal between the two groups. Compared to the lidocaine group, the patients in Jinhoujian group had significantly lower scores of NRS (P=0.027), Prince-Henry (P=0.002), and oral mucositis (P=0.026) 24 h after laryngeal mask removal . ConclusionsJinhoujian spray can effectively reduce incidence of postoperative nausea and vomiting, alleviate POST and oral mucositis 24 h after laryngeal mask removal, improving patient comfort after lower limb fracture surgery.https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2024.20241126jinhoujian aerosollidocaine aerosolhemodynamicssore throatoral mucositis
spellingShingle Lei WU
Yuanhua ZHENG
Ningzhe KANG
Yimeng XIA
Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantation
Zhongguo Linchuang Yixue
jinhoujian aerosol
lidocaine aerosol
hemodynamics
sore throat
oral mucositis
title Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantation
title_full Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantation
title_fullStr Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantation
title_full_unstemmed Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantation
title_short Effect of Jinhoujian spray on postoperative complications after non-inflatable laryngeal mask implantation
title_sort effect of jinhoujian spray on postoperative complications after non inflatable laryngeal mask implantation
topic jinhoujian aerosol
lidocaine aerosol
hemodynamics
sore throat
oral mucositis
url https://www.c-jcm.com/article/doi/10.12025/j.issn.1008-6358.2024.20241126
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AT ningzhekang effectofjinhoujiansprayonpostoperativecomplicationsafternoninflatablelaryngealmaskimplantation
AT yimengxia effectofjinhoujiansprayonpostoperativecomplicationsafternoninflatablelaryngealmaskimplantation