Selumetinib in Adult Neurofibromatosis 1 with Plexiform Neurofibroma

Selumetinib in Adult Neurofibromatosis 1 with Plexiform Neurofibroma

<b>Background/Objectives:</b> Neurofibromatosis Type 1 (NF1) plexiform neurofibroma (PN) can cause morbidity, including disfigurement that can negatively impact social functioning. Historically, the mainstay treatment is surgical resection. However, complete resection is often prohibitiv...

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Bibliographic Details
Main Authors: Carlen A. Yuen, Eleanor Chu, Ryan O’Connell, Bryan K. Sun, Raj Vyas, Michelle Zheng, Emma Elliott, Changrui Xiao
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceuticals
Subjects:
neurofibromatosis 1
NF1
selumetinib
adult
plexiform neurofibroma
targeted therapy
Online Access:https://www.mdpi.com/1424-8247/18/7/1039
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