Single-cell transcriptomics reveals heterogeneity and prognostic markers of myeloid precursor cells in acute myeloid leukemia

Single-cell transcriptomics reveals heterogeneity and prognostic markers of myeloid precursor cells in acute myeloid leukemia

BackgroundAcute myeloid leukemia (AML) is a hematologic tumor with poor prognosis and significant clinical heterogeneity. By integrating transcriptomic data, single-cell RNA sequencing data and independently collected RNA sequencing data this study aims to identify key genes in AML and establish a p...

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Bibliographic Details
Main Authors: Guangfeng He, Lai Jiang, Xuancheng Zhou, Yuheng Gu, Jingyi Tang, Qiang Zhang, Qingwen Hu, Gang Huang, Ziye Zhuang, Xinrui Gao, Ke Xu, Yewei Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
acute myeloid leukemia
prognostic biomarkers
immune escape
personalized treatment
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1494106/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1494106/full

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