Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image Registration

Discontinuous displacements pose a substantial challenge to image registration algorithms, which generally assume smooth deformations. Two prominent cases occur in 4DCT lung scans. The first instance exists at the lung-thorax-boundary, where due to high elasticities and expansion properties, lungs e...

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Main Authors: Thomas Alscher, Jens Petersen, Francois Lauze, Kenny Erleben, Sune Darkner
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
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Online Access:https://ieeexplore.ieee.org/document/11079567/
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author Thomas Alscher
Jens Petersen
Francois Lauze
Kenny Erleben
Sune Darkner
author_facet Thomas Alscher
Jens Petersen
Francois Lauze
Kenny Erleben
Sune Darkner
author_sort Thomas Alscher
collection DOAJ
description Discontinuous displacements pose a substantial challenge to image registration algorithms, which generally assume smooth deformations. Two prominent cases occur in 4DCT lung scans. The first instance exists at the lung-thorax-boundary, where due to high elasticities and expansion properties, lungs exhibit higher displacements than the surrounding thoracic cavity, leading to sliding motions along their interface. Discontinuous motion is facilitated through a piecewise registration framework, in which inter-domain boundary interactions are constrained via collision detection, and intra-domain deformation smoothness is governed by the Large Deformation Diffeomorphic Metric Mapping (LDDMM) model. The second case with discontinuous displacements is found between lung lobes along the separating lung fissures. A fissure reconstruction algorithm for sparse segmentation is presented, improving geometric lung representation. Utilizing a refined Free-Form Deformation model for lobe-on-lobe registration that permits lobar sliding and prevents self-intersection, this approach examines discontinuities around the pulmonary fissures. Both cases are evaluated on synthetic and medical data, with boundary inconsistency results and average registration metrics on the DIRLAB dataset comparable to other approaches addressing sliding motion.
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spelling doaj-art-1ff3f10a961c4be1a4f4518fe2a00b6b2025-08-20T03:41:52ZengIEEEIEEE Access2169-35362025-01-011313923613925510.1109/ACCESS.2025.358876011079567Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image RegistrationThomas Alscher0https://orcid.org/0000-0002-0948-7287Jens Petersen1Francois Lauze2https://orcid.org/0000-0003-2503-6475Kenny Erleben3https://orcid.org/0000-0001-6808-4747Sune Darkner4Department of Computer Science, University of Copenhagen, Copenhagen, DenmarkDepartment of Computer Science, University of Copenhagen, Copenhagen, DenmarkDepartment of Computer Science, University of Copenhagen, Copenhagen, DenmarkDepartment of Computer Science, University of Copenhagen, Copenhagen, DenmarkDepartment of Computer Science, University of Copenhagen, Copenhagen, DenmarkDiscontinuous displacements pose a substantial challenge to image registration algorithms, which generally assume smooth deformations. Two prominent cases occur in 4DCT lung scans. The first instance exists at the lung-thorax-boundary, where due to high elasticities and expansion properties, lungs exhibit higher displacements than the surrounding thoracic cavity, leading to sliding motions along their interface. Discontinuous motion is facilitated through a piecewise registration framework, in which inter-domain boundary interactions are constrained via collision detection, and intra-domain deformation smoothness is governed by the Large Deformation Diffeomorphic Metric Mapping (LDDMM) model. The second case with discontinuous displacements is found between lung lobes along the separating lung fissures. A fissure reconstruction algorithm for sparse segmentation is presented, improving geometric lung representation. Utilizing a refined Free-Form Deformation model for lobe-on-lobe registration that permits lobar sliding and prevents self-intersection, this approach examines discontinuities around the pulmonary fissures. Both cases are evaluated on synthetic and medical data, with boundary inconsistency results and average registration metrics on the DIRLAB dataset comparable to other approaches addressing sliding motion.https://ieeexplore.ieee.org/document/11079567/Deformable image registrationLDDMMdiscontinuitiescollision detection
spellingShingle Thomas Alscher
Jens Petersen
Francois Lauze
Kenny Erleben
Sune Darkner
Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image Registration
IEEE Access
Deformable image registration
LDDMM
discontinuities
collision detection
title Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image Registration
title_full Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image Registration
title_fullStr Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image Registration
title_full_unstemmed Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image Registration
title_short Collision Constraints and Diffeomorphisms: Dealing With Physics in Deformable Image Registration
title_sort collision constraints and diffeomorphisms dealing with physics in deformable image registration
topic Deformable image registration
LDDMM
discontinuities
collision detection
url https://ieeexplore.ieee.org/document/11079567/
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AT kennyerleben collisionconstraintsanddiffeomorphismsdealingwithphysicsindeformableimageregistration
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