Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter Rot

The application of synthetic fungicides has resulted in environmental pollution and adverse effects on non-target species. To reduce the use of agrochemicals, crop disease management requires microbial biological control agents. Bacillus-related genera produce secondary metabolites to control fungal...

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Main Authors: Hyeonjin Park, Younmi Lee, Kotnala Balaraju, Jungyeon Kim, Yongho Jeon
Format: Article
Language:English
Published: Hanrimwon Publishing Company 2024-12-01
Series:The Plant Pathology Journal
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Online Access:http://ppjonline.org/upload/pdf/PPJ-OA-05-2024-0076.pdf
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author Hyeonjin Park
Younmi Lee
Kotnala Balaraju
Jungyeon Kim
Yongho Jeon
author_facet Hyeonjin Park
Younmi Lee
Kotnala Balaraju
Jungyeon Kim
Yongho Jeon
author_sort Hyeonjin Park
collection DOAJ
description The application of synthetic fungicides has resulted in environmental pollution and adverse effects on non-target species. To reduce the use of agrochemicals, crop disease management requires microbial biological control agents. Bacillus-related genera produce secondary metabolites to control fungal pathogens. Bacillus velezensis GYUN-1190, isolated from soil, showed antagonistic activity against Colletotrichum fructicola, the apple anthracnose pathogen. Volatile organic compounds and culture filtrate (CF) from GYUN-1190 inhibited C. fructicola growth in vitro, by 80.9% and 30.25%, respectively. The CF of GYUN-1190 inhibited pathogen spore germination more than cell suspensions at 108 cfu/ml. Furthermore, GYUN-1190 CF is effective in inhibiting C. fructicola mycelial growth in vitro, and it suppresses apple fruit bitter rot more effectively than GYUN-1190 cell suspensions and pyraclostrobin in planta. The mycelial growth of C. fructicola was completely inhibited 48 h after immersion into the CF, in compared with positive controls and GYUN-1190 cell suspensions. The genetic mechanism underlying the biocontrol features of GYUN-1190 was defined using its whole-genome sequence, which was closely compared to similar strains. It consisted of 4,240,653 bp with 45.9% GC content, with 4,142 coding sequences, 87 tRNA, and 28 rRNA genes. The genomic investigation found 14 putative secondary metabolite biosynthetic gene clusters. The investigation suggests that B. velezensis GYUN-1190 might be more effective than chemical fungicides and could address its potential as a biological control agent.
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spelling doaj-art-1fcd8be13cb14e2c8c8aab59bf43278a2024-12-06T07:37:43ZengHanrimwon Publishing CompanyThe Plant Pathology Journal1598-22542093-92802024-12-0140668169510.5423/PPJ.OA.05.2024.00762483Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter RotHyeonjin Park0Younmi Lee1Kotnala Balaraju2Jungyeon Kim3Yongho Jeon4 Department of Plant Medicals, Andong National University, Andong 36729, Korea Department of Plant Medicals, Andong National University, Andong 36729, Korea Agricultural Science and Technology Research Institute, Andong National University, Andong 36729, Korea Department of Plant Medicals, Andong National University, Andong 36729, Korea Department of Plant Medicals, Andong National University, Andong 36729, KoreaThe application of synthetic fungicides has resulted in environmental pollution and adverse effects on non-target species. To reduce the use of agrochemicals, crop disease management requires microbial biological control agents. Bacillus-related genera produce secondary metabolites to control fungal pathogens. Bacillus velezensis GYUN-1190, isolated from soil, showed antagonistic activity against Colletotrichum fructicola, the apple anthracnose pathogen. Volatile organic compounds and culture filtrate (CF) from GYUN-1190 inhibited C. fructicola growth in vitro, by 80.9% and 30.25%, respectively. The CF of GYUN-1190 inhibited pathogen spore germination more than cell suspensions at 108 cfu/ml. Furthermore, GYUN-1190 CF is effective in inhibiting C. fructicola mycelial growth in vitro, and it suppresses apple fruit bitter rot more effectively than GYUN-1190 cell suspensions and pyraclostrobin in planta. The mycelial growth of C. fructicola was completely inhibited 48 h after immersion into the CF, in compared with positive controls and GYUN-1190 cell suspensions. The genetic mechanism underlying the biocontrol features of GYUN-1190 was defined using its whole-genome sequence, which was closely compared to similar strains. It consisted of 4,240,653 bp with 45.9% GC content, with 4,142 coding sequences, 87 tRNA, and 28 rRNA genes. The genomic investigation found 14 putative secondary metabolite biosynthetic gene clusters. The investigation suggests that B. velezensis GYUN-1190 might be more effective than chemical fungicides and could address its potential as a biological control agent.http://ppjonline.org/upload/pdf/PPJ-OA-05-2024-0076.pdfanthracnosebacillus velezensisbiocontrolcolletotrichumgrowth inhibition
spellingShingle Hyeonjin Park
Younmi Lee
Kotnala Balaraju
Jungyeon Kim
Yongho Jeon
Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter Rot
The Plant Pathology Journal
anthracnose
bacillus velezensis
biocontrol
colletotrichum
growth inhibition
title Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter Rot
title_full Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter Rot
title_fullStr Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter Rot
title_full_unstemmed Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter Rot
title_short Characterization and Biocontrol Efficacy of Bacillus velezensis GYUN-1190 against Apple Bitter Rot
title_sort characterization and biocontrol efficacy of bacillus velezensis gyun 1190 against apple bitter rot
topic anthracnose
bacillus velezensis
biocontrol
colletotrichum
growth inhibition
url http://ppjonline.org/upload/pdf/PPJ-OA-05-2024-0076.pdf
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