Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report

Introduction. During the last few years, intravenous lipid emulsions have been effectively used in treatment of acute poisonings with lipophilic substances, including verapamil. Case report. A 37-year-old women presented 1 hour after ingestion of 2.8 g verapamil with hypotension and complet...

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Main Authors: Vuković-Ercegović Gordana, Perković-Vukčević Nataša, Đorđević Snežana, Šegrt Zoran, Potrebić Olivera, Janković Snežana R., Jović-Stošić Jasmina, Marinković Nadica
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2017-01-01
Series:Vojnosanitetski Pregled
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Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600010V.pdf
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author Vuković-Ercegović Gordana
Perković-Vukčević Nataša
Đorđević Snežana
Šegrt Zoran
Potrebić Olivera
Janković Snežana R.
Jović-Stošić Jasmina
Marinković Nadica
author_facet Vuković-Ercegović Gordana
Perković-Vukčević Nataša
Đorđević Snežana
Šegrt Zoran
Potrebić Olivera
Janković Snežana R.
Jović-Stošić Jasmina
Marinković Nadica
author_sort Vuković-Ercegović Gordana
collection DOAJ
description Introduction. During the last few years, intravenous lipid emulsions have been effectively used in treatment of acute poisonings with lipophilic substances, including verapamil. Case report. A 37-year-old women presented 1 hour after ingestion of 2.8 g verapamil with hypotension and complete heart block. Because of the applied standard therapy failure and further patients impairment, Intralipid® 20% was used. Sinus rhythm was restored, arterial blood pressure increased and verapamile concentrations, both total and free decreased. Conclusion. Intravenous lipid emulsion can be important in treatment of severe acute intoxication and cardiotoxicity caused by verapamil.
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issn 0042-8450
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language English
publishDate 2017-01-01
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series Vojnosanitetski Pregled
spelling doaj-art-1fa8a6040ef34b3d8e44bd4bca4fa6882025-08-20T03:17:35ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202017-01-0174327828110.2298/VSP150901010V0042-84501600010VSuccessful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case reportVuković-Ercegović Gordana0Perković-Vukčević Nataša1Đorđević Snežana2Šegrt Zoran3Potrebić Olivera4Janković Snežana R.5Jović-Stošić Jasmina6Marinković Nadica7Military Medical Academy, National Poison Control Center, BelgradeMilitary Medical Academy, National Poison Control Center, BelgradeMilitary Medical Academy, National Poison Control Center, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, National Poison Control Center, BelgradeMilitary Medical Academy, Institute for Scientific Information, BelgradeMilitary Medical Academy, National Poison Control Center, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute of Pathology and Forensic Medicine, BelgradeIntroduction. During the last few years, intravenous lipid emulsions have been effectively used in treatment of acute poisonings with lipophilic substances, including verapamil. Case report. A 37-year-old women presented 1 hour after ingestion of 2.8 g verapamil with hypotension and complete heart block. Because of the applied standard therapy failure and further patients impairment, Intralipid® 20% was used. Sinus rhythm was restored, arterial blood pressure increased and verapamile concentrations, both total and free decreased. Conclusion. Intravenous lipid emulsion can be important in treatment of severe acute intoxication and cardiotoxicity caused by verapamil.http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600010V.pdfpoisoningsuicideverapamilcalcium channel blockersheart blockfat emulsions, intravenoustreatment outcome
spellingShingle Vuković-Ercegović Gordana
Perković-Vukčević Nataša
Đorđević Snežana
Šegrt Zoran
Potrebić Olivera
Janković Snežana R.
Jović-Stošić Jasmina
Marinković Nadica
Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report
Vojnosanitetski Pregled
poisoning
suicide
verapamil
calcium channel blockers
heart block
fat emulsions, intravenous
treatment outcome
title Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report
title_full Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report
title_fullStr Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report
title_full_unstemmed Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report
title_short Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report
title_sort successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning a case report
topic poisoning
suicide
verapamil
calcium channel blockers
heart block
fat emulsions, intravenous
treatment outcome
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600010V.pdf
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