Targeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically ‘cold’ tumor models

Targeted intra-tumoral hyperthermia using uniquely biocompatible gold nanorods induces strong immunogenic cell death in two immunogenically ‘cold’ tumor models

IntroductionHyperthermia is an established adjunct in multimodal cancer treatments, with mechanisms including cell death, immune modulation, and vascular changes. Traditional hyperthermia applications are resource-intensive and often associated with patient morbidity, limiting their clinical accessi...

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Bibliographic Details
Main Authors: Barry E. Kennedy, Erin B. Noftall, Cheryl Dean, Alexander Roth, Kate N. Clark, Darren Rowles, Kulbir Singh, Len Pagliaro, Carman A. Giacomantonio
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
gold nanorods
hyperthermia
immunotherapy
interleukin-2
photothermal therapy
breast cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1512543/full
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