Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management

Diabetes mellitus presents a significant global health challenge by substantially increasing the risk of developing cardiovascular disease (CVD). This review delves into the pathophysiological mechanisms that underlie this association, exploring the contributions of chronic hyperglycemia, insulin re...

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Main Author: Omar Elsaka
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-10-01
Series:Journal of Clinical and Preventive Cardiology
Subjects:
Online Access:https://journals.lww.com/10.4103/jcpc.jcpc_8_24
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author Omar Elsaka
author_facet Omar Elsaka
author_sort Omar Elsaka
collection DOAJ
description Diabetes mellitus presents a significant global health challenge by substantially increasing the risk of developing cardiovascular disease (CVD). This review delves into the pathophysiological mechanisms that underlie this association, exploring the contributions of chronic hyperglycemia, insulin resistance, and other factors to the development and progression of CVD in individuals with diabetes. Furthermore, the review evaluates current management strategies, including glycemic control, blood pressure management, lipid management, and antiplatelet therapy, emphasizing their critical role in mitigating cardiovascular risk and improving patient outcomes.
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institution Kabale University
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publisher Wolters Kluwer Medknow Publications
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series Journal of Clinical and Preventive Cardiology
spelling doaj-art-1f9dd9b981664fc4b6780294ea988ba82025-01-10T12:18:48ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Preventive Cardiology2250-35282024-10-01133637010.4103/jcpc.jcpc_8_24Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and ManagementOmar ElsakaDiabetes mellitus presents a significant global health challenge by substantially increasing the risk of developing cardiovascular disease (CVD). This review delves into the pathophysiological mechanisms that underlie this association, exploring the contributions of chronic hyperglycemia, insulin resistance, and other factors to the development and progression of CVD in individuals with diabetes. Furthermore, the review evaluates current management strategies, including glycemic control, blood pressure management, lipid management, and antiplatelet therapy, emphasizing their critical role in mitigating cardiovascular risk and improving patient outcomes.https://journals.lww.com/10.4103/jcpc.jcpc_8_24antiplatelet therapyblood pressure controlcardiovascular diseasediabetes mellitusglycemic controlhyperglycemiainsulin resistancelipid managementmanagementpathophysiology
spellingShingle Omar Elsaka
Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management
Journal of Clinical and Preventive Cardiology
antiplatelet therapy
blood pressure control
cardiovascular disease
diabetes mellitus
glycemic control
hyperglycemia
insulin resistance
lipid management
management
pathophysiology
title Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management
title_full Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management
title_fullStr Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management
title_full_unstemmed Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management
title_short Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management
title_sort cardiovascular effects of diabetes mellitus a review of pathophysiology and management
topic antiplatelet therapy
blood pressure control
cardiovascular disease
diabetes mellitus
glycemic control
hyperglycemia
insulin resistance
lipid management
management
pathophysiology
url https://journals.lww.com/10.4103/jcpc.jcpc_8_24
work_keys_str_mv AT omarelsaka cardiovasculareffectsofdiabetesmellitusareviewofpathophysiologyandmanagement