Viral coexistence and insertional mutations in the ORF8 region of SARS-CoV-2: A possible mechanism of nucleotide insertion

Viral coexistence and insertional mutations in the ORF8 region of SARS-CoV-2: A possible mechanism of nucleotide insertion

The virus obtained from a swab sample ID: S66 in Hiroshima was reported to have a single T-base insertion in the ORF8 coding region. However, no T insertion was observed when we determined the genomic sequence using another method. We then extracted RNA from the S66 swab sample and sequenced the ins...

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Bibliographic Details
Main Authors: Miuko Kurose, Akima Yamamoto, Abeer Mohamed Abdelfattah Elsayed, Basirat Mojisola Lawal-Ayinde, Toshihito Nomura, Akifumi Higashiura, Takashi Irie, Masaya Fukushi, Miyuki Kanda, Hidetoshi Tahara, Daichi Morita, Teruo Kuroda, Ko Ko, Kazuaki Takahashi, Junko Tanaka, Takemasa Sakaguchi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Virus Research
Subjects:
Covid-19
Polymerase stuttering
T-base insertions
NGS analysis
TIDE analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170224001710
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