Exploring the effects of exercise on immune cell function and tumour infiltration in patients with breast cancer receiving neoadjuvant chemotherapy – a feasibility trial

Exploring the effects of exercise on immune cell function and tumour infiltration in patients with breast cancer receiving neoadjuvant chemotherapy – a feasibility trial

Pre-clinical studies have shown that exercise can decrease tumour growth through mobilisation, activation, and increased tumour infiltration of natural killer (NK) and CD8+ T cells. It is currently unclear whether this can be extrapolated to patients. Therefore, a pilot study was set up to examine t...

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Main Authors: Anna Ubink, Marieke R. ten Tusscher, Hans J. van der Vliet, Joeri A.J. Douma, Tanja D. de Gruijl, Hetty Bontkes, Petra Bonnet, Diede van Ens, Willemijn Hobo, Harry Dolstra, Ellis Barbé, Susanne van der Velde, Catharina Willemien Menke-van der Houven van Oordt, Simone H.C. Havenith, Annemarie Conijn-Mensink, Annette A. van Zweeden, Harm Westdorp, Joannes F.M. Jacobs, Laurien M. Buffart
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Exercise
Immune monitoring
Cancer
Chemotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354625000791
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