Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of Gaza

Warfarin is widely prescribed for the prevention of thromboembolic events but carries a well-known risk of bleeding complications. While gastrointestinal and intracranial hemorrhages remain among the more frequent sites, pulmonary hemorrhage is an exceedingly rare case presentation and can be partic...

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Main Authors: Abdallah Abu Shammala, Majed Jaber, Bilal Irfan, Alaa Owda, Abdallah Herzallah
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Case Reports in Pulmonology
Online Access:http://dx.doi.org/10.1155/crpu/8866411
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author Abdallah Abu Shammala
Majed Jaber
Bilal Irfan
Alaa Owda
Abdallah Herzallah
author_facet Abdallah Abu Shammala
Majed Jaber
Bilal Irfan
Alaa Owda
Abdallah Herzallah
author_sort Abdallah Abu Shammala
collection DOAJ
description Warfarin is widely prescribed for the prevention of thromboembolic events but carries a well-known risk of bleeding complications. While gastrointestinal and intracranial hemorrhages remain among the more frequent sites, pulmonary hemorrhage is an exceedingly rare case presentation and can be particularly catastrophic. We report the case of a 57-year-old male in Gaza with an extensive medical history of past hospitalization, who presented with severe ecchymosis, with his condition progressing to life-threatening pulmonary hemorrhage. This case occurred amid an active Israeli military assault in November 2024 in the European Gaza Hospital in Khan Yunis, at a time when diagnostic modalities had become limited or completely destroyed and healthcare resources were in severe shortage. The patient was treated with supportive measures, including mechanical ventilation and warfarin reversal using vitamin K and fresh frozen plasma. His anticoagulation regimen was changed to rivaroxaban. This case underlines the difficulties in diagnosing and managing rare but critical hemorrhagic complications in conflict-affected regions and emphasizes the urgency for clinicians to be vigilantly monitoring international normalized ratio values to conduct timely interventions.
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institution Kabale University
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series Case Reports in Pulmonology
spelling doaj-art-1f367639c1e849be90f1b7f1d1782ee82025-08-25T00:00:05ZengWileyCase Reports in Pulmonology2090-68542025-01-01202510.1155/crpu/8866411Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of GazaAbdallah Abu Shammala0Majed Jaber1Bilal Irfan2Alaa Owda3Abdallah Herzallah4Department of Internal MedicineDepartment of Internal MedicineDepartment of NeurologyDepartment of Internal MedicineDepartment of Internal MedicineWarfarin is widely prescribed for the prevention of thromboembolic events but carries a well-known risk of bleeding complications. While gastrointestinal and intracranial hemorrhages remain among the more frequent sites, pulmonary hemorrhage is an exceedingly rare case presentation and can be particularly catastrophic. We report the case of a 57-year-old male in Gaza with an extensive medical history of past hospitalization, who presented with severe ecchymosis, with his condition progressing to life-threatening pulmonary hemorrhage. This case occurred amid an active Israeli military assault in November 2024 in the European Gaza Hospital in Khan Yunis, at a time when diagnostic modalities had become limited or completely destroyed and healthcare resources were in severe shortage. The patient was treated with supportive measures, including mechanical ventilation and warfarin reversal using vitamin K and fresh frozen plasma. His anticoagulation regimen was changed to rivaroxaban. This case underlines the difficulties in diagnosing and managing rare but critical hemorrhagic complications in conflict-affected regions and emphasizes the urgency for clinicians to be vigilantly monitoring international normalized ratio values to conduct timely interventions.http://dx.doi.org/10.1155/crpu/8866411
spellingShingle Abdallah Abu Shammala
Majed Jaber
Bilal Irfan
Alaa Owda
Abdallah Herzallah
Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of Gaza
Case Reports in Pulmonology
title Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of Gaza
title_full Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of Gaza
title_fullStr Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of Gaza
title_full_unstemmed Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of Gaza
title_short Warfarin-Induced Pulmonary Hemorrhage: A Rare and Life-Threatening Complication in the Resource-Limited Setting of Gaza
title_sort warfarin induced pulmonary hemorrhage a rare and life threatening complication in the resource limited setting of gaza
url http://dx.doi.org/10.1155/crpu/8866411
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