Ferroptosis-related gene signature-based subtype identification of triple-negative breast cancer to prioritize treatment strategies

Ferroptosis-related gene signature-based subtype identification of triple-negative breast cancer to prioritize treatment strategies

PurposeFerroptosis, an iron-dependent form of regulated cell death (RCD), has been proven to affect the response to antineoplastic therapies. However, little is known about the role of ferroptosis in chemotherapy and immune checkpoint inhibitor (ICI) therapy responses, as well as the molecular subty...

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Bibliographic Details
Main Authors: Yongzhen Chen, Xiaoying Huang, Junqi Wang, Chao Hu, Yanan Zheng, Yumeng Wang, Shuqian Zheng, Guozhong Ji, Qiang You
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
ferroptosis
triple-negative breast cancer
molecular subtype
immunotherapy
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1541119/full
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