Identification of a serum proteomic biomarker panel using diagnosis specific ensemble learning and symptoms for early pancreatic cancer detection.

Identification of a serum proteomic biomarker panel using diagnosis specific ensemble learning and symptoms for early pancreatic cancer detection.

<h4>Background</h4>The grim (<10% 5-year) survival rates for pancreatic ductal adenocarcinoma (PDAC) are attributed to its complex intrinsic biology and most often late-stage detection. The overlap of symptoms with benign gastrointestinal conditions in early stage further complicates...

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Main Authors: Alexander Ney, Nuno R Nené, Eva Sedlak, Pilar Acedo, Oleg Blyuss, Harry J Whitwell, Eithne Costello, Aleksandra Gentry-Maharaj, Norman R Williams, Usha Menon, Giuseppe K Fusai, Alexey Zaikin, Stephen P Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012408
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