ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDREN

The article presents modern data on etiology of acute and chronic inflammatory diseases of airways in children. Special attention is given to the treatment with oral antibiotics and to the meaning of these drugs. Authors give a literature review of biological, pharmacokinetic and anti-microbal activ...

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Main Authors: Ye.V. Sereda, L.K. Katosova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2011-05-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/625
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author Ye.V. Sereda
L.K. Katosova
author_facet Ye.V. Sereda
L.K. Katosova
author_sort Ye.V. Sereda
collection DOAJ
description The article presents modern data on etiology of acute and chronic inflammatory diseases of airways in children. Special attention is given to the treatment with oral antibiotics and to the meaning of these drugs. Authors give a literature review of biological, pharmacokinetic and anti-microbal activities of macrolides and particularly azithromycin. Detailed characteristics of effects of macrolide antibiotic azithromycin and tactics of its administration for the treatment of airways diseases in children are presented. The article describes nonantibacterial effects of azithromycin: anti-inflammatory, immunomodulatory and mucoregulatory ones. New activities of azithromycin are structural and functional defence of respiratory epithelium and ability to prevent adhesia of microorganisms. These properties of a drug widen the indications of its administration. The reasonability of its use for treatment of out-of-hospital pneumonias including atypical ones (mycoplasmal and chlamidia pneumonias) and in patients with exacerbations of chronic inflammatory bronchopulmonary diseases was show.Key words: children, acute and chronic respiratory diseases, pneumococcus, hemophilus influenza, azithromycin.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (3): 124–130)
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institution Kabale University
issn 1682-5527
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language English
publishDate 2011-05-01
publisher "Paediatrician" Publishers LLC
record_format Article
series Вопросы современной педиатрии
spelling doaj-art-1f0c61a9d2684c75aa4a6976cdfbf07f2025-08-20T03:59:52Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352011-05-01103625ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDRENYe.V. Sereda0L.K. Katosova1Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowThe article presents modern data on etiology of acute and chronic inflammatory diseases of airways in children. Special attention is given to the treatment with oral antibiotics and to the meaning of these drugs. Authors give a literature review of biological, pharmacokinetic and anti-microbal activities of macrolides and particularly azithromycin. Detailed characteristics of effects of macrolide antibiotic azithromycin and tactics of its administration for the treatment of airways diseases in children are presented. The article describes nonantibacterial effects of azithromycin: anti-inflammatory, immunomodulatory and mucoregulatory ones. New activities of azithromycin are structural and functional defence of respiratory epithelium and ability to prevent adhesia of microorganisms. These properties of a drug widen the indications of its administration. The reasonability of its use for treatment of out-of-hospital pneumonias including atypical ones (mycoplasmal and chlamidia pneumonias) and in patients with exacerbations of chronic inflammatory bronchopulmonary diseases was show.Key words: children, acute and chronic respiratory diseases, pneumococcus, hemophilus influenza, azithromycin.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (3): 124–130)https://vsp.spr-journal.ru/jour/article/view/625
spellingShingle Ye.V. Sereda
L.K. Katosova
ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDREN
Вопросы современной педиатрии
title ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDREN
title_full ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDREN
title_fullStr ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDREN
title_full_unstemmed ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDREN
title_short ETIOLOGY AND INNOVATIVE APPROACH TO THE TREATMENT OF ACUTE AND CHRONIC INFECTIOUS INFLAMMATORY DISEASES OF BRONCHOPULMONARY SYSTEM IN CHILDREN
title_sort etiology and innovative approach to the treatment of acute and chronic infectious inflammatory diseases of bronchopulmonary system in children
url https://vsp.spr-journal.ru/jour/article/view/625
work_keys_str_mv AT yevsereda etiologyandinnovativeapproachtothetreatmentofacuteandchronicinfectiousinflammatorydiseasesofbronchopulmonarysysteminchildren
AT lkkatosova etiologyandinnovativeapproachtothetreatmentofacuteandchronicinfectiousinflammatorydiseasesofbronchopulmonarysysteminchildren