EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT)
The osteoporosis model of mouse tibia was established based on castration, and the effect of osteoporosis on the mechanical properties of tibia was investigated. The two-dimensional sections of mouse tibia were obtained by Micro-CT. The three-dimensional digital model of mouse tibia was obtained by...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Mechanical Strength
2023-01-01
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| Series: | Jixie qiangdu |
| Subjects: | |
| Online Access: | http://www.jxqd.net.cn/thesisDetails#10.16579/j.issn.1001.9669.2023.01.009 |
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| _version_ | 1841534304145899520 |
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| author | ZHAO Qing YIN ZiYang ZHOU Wen REN GuanLin KUANG ChunMei HU Cong ZHOU ChangJiang |
| author_facet | ZHAO Qing YIN ZiYang ZHOU Wen REN GuanLin KUANG ChunMei HU Cong ZHOU ChangJiang |
| author_sort | ZHAO Qing |
| collection | DOAJ |
| description | The osteoporosis model of mouse tibia was established based on castration, and the effect of osteoporosis on the mechanical properties of tibia was investigated. The two-dimensional sections of mouse tibia were obtained by Micro-CT. The three-dimensional digital model of mouse tibia was obtained by reconstruction technology, and trabecular bone shape and density were analyzed. The effect of osteoporosis on the mechanical properties of tibia was explored by testing and finite element simulation. The results showed that osteoporosis could damage the trabecular structure and decrease the mechanical properties of tibia. Compared with healthy tibia, the maximum load, bending stiffness and elastic modulus of tibia decreased by 20%, 30% and 25%, respectively, and the simulation results were in good agreement with the experiment. This study provides an important basis for the clinical diagnosis and treatment of osteoporosis. |
| format | Article |
| id | doaj-art-1ef05dd0409e4ad983aa26960cb48207 |
| institution | Kabale University |
| issn | 1001-9669 |
| language | zho |
| publishDate | 2023-01-01 |
| publisher | Editorial Office of Journal of Mechanical Strength |
| record_format | Article |
| series | Jixie qiangdu |
| spelling | doaj-art-1ef05dd0409e4ad983aa26960cb482072025-01-15T02:40:25ZzhoEditorial Office of Journal of Mechanical StrengthJixie qiangdu1001-96692023-01-01687536350246EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT)ZHAO QingYIN ZiYangZHOU WenREN GuanLinKUANG ChunMeiHU CongZHOU ChangJiangThe osteoporosis model of mouse tibia was established based on castration, and the effect of osteoporosis on the mechanical properties of tibia was investigated. The two-dimensional sections of mouse tibia were obtained by Micro-CT. The three-dimensional digital model of mouse tibia was obtained by reconstruction technology, and trabecular bone shape and density were analyzed. The effect of osteoporosis on the mechanical properties of tibia was explored by testing and finite element simulation. The results showed that osteoporosis could damage the trabecular structure and decrease the mechanical properties of tibia. Compared with healthy tibia, the maximum load, bending stiffness and elastic modulus of tibia decreased by 20%, 30% and 25%, respectively, and the simulation results were in good agreement with the experiment. This study provides an important basis for the clinical diagnosis and treatment of osteoporosis.http://www.jxqd.net.cn/thesisDetails#10.16579/j.issn.1001.9669.2023.01.009Mouse tibiaOsteoporosisMechanical propertiesFinite element simulation |
| spellingShingle | ZHAO Qing YIN ZiYang ZHOU Wen REN GuanLin KUANG ChunMei HU Cong ZHOU ChangJiang EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT) Jixie qiangdu Mouse tibia Osteoporosis Mechanical properties Finite element simulation |
| title | EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT) |
| title_full | EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT) |
| title_fullStr | EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT) |
| title_full_unstemmed | EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT) |
| title_short | EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT) |
| title_sort | experiment and simulation on mechanical properties of osteoporotic mouse bone mt |
| topic | Mouse tibia Osteoporosis Mechanical properties Finite element simulation |
| url | http://www.jxqd.net.cn/thesisDetails#10.16579/j.issn.1001.9669.2023.01.009 |
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