L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer

L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer

Abstract The STAT3 pathway promotes epithelial–mesenchymal transition, migration, invasion and metastasis in cancer. STAT3 upregulates the transcription of the key epithelial–mesenchymal transition transcription factor SNAIL in a DNA binding-independent manner. However, the mechanism by which STAT3...

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Main Authors: Jianpeng Xiao, Jie Wang, Jialun Li, Jie Xiao, CuiCui Liu, Libi Tan, Yanhong Tu, Ruifang Yang, Yujie Pei, Minghua Wang, Jiemin Wong, Binhua P. Zhou, Jing Li, Jing Feng
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55617-9
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