Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of China

Objectives Although there is no consensus on the difference in rupture rates between multiple intracranial aneurysms (MIAs) and single intracranial aneurysms (SIAs), patients with MIAs may have poorer outcomes after rupture than patients with SIAs. In this study, we aimed to analyze differences in c...

Full description

Saved in:
Bibliographic Details
Main Authors: Dongliang Wang, Jiuqi Wuli, Xudong Cao, Bin Wang, Zeng Ren, Yu Weng, Kexue Wu
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605241306870
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846100508508422144
author Dongliang Wang
Jiuqi Wuli
Xudong Cao
Bin Wang
Zeng Ren
Yu Weng
Kexue Wu
author_facet Dongliang Wang
Jiuqi Wuli
Xudong Cao
Bin Wang
Zeng Ren
Yu Weng
Kexue Wu
author_sort Dongliang Wang
collection DOAJ
description Objectives Although there is no consensus on the difference in rupture rates between multiple intracranial aneurysms (MIAs) and single intracranial aneurysms (SIAs), patients with MIAs may have poorer outcomes after rupture than patients with SIAs. In this study, we aimed to analyze differences in clinical characteristics between MIAs and SIAs and to evaluate the prognosis of patients with MIAs on the Tibetan Plateau who received different clinical treatments. Methods We retrospectively analyzed the clinical data of 68 patients with MIAs and 68 patients with SIAs admitted to Tibet Autonomous Region People’s Hospital. Univariate and multivariate analyses were used for data analysis. Results Compared with patients who had SIAs, those with MIAs were more likely to be female, smokers, alcohol drinkers, and hypertensive. The difference between the two groups in terms of size of the ruptured aneurysms was statistically significant. No significant differences in treatment effects were observed between patients with SIAs and those with MIAs at 3, 6, and 12 months. Conclusions Among patients living on the Tibetan Plateau, those with MIAs were more likely to be female, smokers, alcohol drinkers, and hypertensive. Endovascular treatment was superior to conservative management but not significantly better than craniotomy.
format Article
id doaj-art-1ec5b8bbcdf341618b955a64b5bdd291
institution Kabale University
issn 1473-2300
language English
publishDate 2024-12-01
publisher SAGE Publishing
record_format Article
series Journal of International Medical Research
spelling doaj-art-1ec5b8bbcdf341618b955a64b5bdd2912024-12-30T06:05:07ZengSAGE PublishingJournal of International Medical Research1473-23002024-12-015210.1177/03000605241306870Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of ChinaDongliang WangJiuqi WuliXudong CaoBin WangZeng RenYu WengKexue WuObjectives Although there is no consensus on the difference in rupture rates between multiple intracranial aneurysms (MIAs) and single intracranial aneurysms (SIAs), patients with MIAs may have poorer outcomes after rupture than patients with SIAs. In this study, we aimed to analyze differences in clinical characteristics between MIAs and SIAs and to evaluate the prognosis of patients with MIAs on the Tibetan Plateau who received different clinical treatments. Methods We retrospectively analyzed the clinical data of 68 patients with MIAs and 68 patients with SIAs admitted to Tibet Autonomous Region People’s Hospital. Univariate and multivariate analyses were used for data analysis. Results Compared with patients who had SIAs, those with MIAs were more likely to be female, smokers, alcohol drinkers, and hypertensive. The difference between the two groups in terms of size of the ruptured aneurysms was statistically significant. No significant differences in treatment effects were observed between patients with SIAs and those with MIAs at 3, 6, and 12 months. Conclusions Among patients living on the Tibetan Plateau, those with MIAs were more likely to be female, smokers, alcohol drinkers, and hypertensive. Endovascular treatment was superior to conservative management but not significantly better than craniotomy.https://doi.org/10.1177/03000605241306870
spellingShingle Dongliang Wang
Jiuqi Wuli
Xudong Cao
Bin Wang
Zeng Ren
Yu Weng
Kexue Wu
Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of China
Journal of International Medical Research
title Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of China
title_full Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of China
title_fullStr Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of China
title_full_unstemmed Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of China
title_short Clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the Tibetan Plateau of China
title_sort clinical characteristics and prognosis of patients with multiple intracranial aneurysms living on the tibetan plateau of china
url https://doi.org/10.1177/03000605241306870
work_keys_str_mv AT dongliangwang clinicalcharacteristicsandprognosisofpatientswithmultipleintracranialaneurysmslivingonthetibetanplateauofchina
AT jiuqiwuli clinicalcharacteristicsandprognosisofpatientswithmultipleintracranialaneurysmslivingonthetibetanplateauofchina
AT xudongcao clinicalcharacteristicsandprognosisofpatientswithmultipleintracranialaneurysmslivingonthetibetanplateauofchina
AT binwang clinicalcharacteristicsandprognosisofpatientswithmultipleintracranialaneurysmslivingonthetibetanplateauofchina
AT zengren clinicalcharacteristicsandprognosisofpatientswithmultipleintracranialaneurysmslivingonthetibetanplateauofchina
AT yuweng clinicalcharacteristicsandprognosisofpatientswithmultipleintracranialaneurysmslivingonthetibetanplateauofchina
AT kexuewu clinicalcharacteristicsandprognosisofpatientswithmultipleintracranialaneurysmslivingonthetibetanplateauofchina