Developmental Programming in Response to Intrauterine Growth Restriction Impairs Myoblast Function and Skeletal Muscle Metabolism

Developmental Programming in Response to Intrauterine Growth Restriction Impairs Myoblast Function and Skeletal Muscle Metabolism

Fetal adaptations to placental insufficiency alter postnatal metabolic homeostasis in skeletal muscle by reducing glucose oxidation rates, impairing insulin action, and lowering the proportion of oxidative fibers. In animal models of intrauterine growth restriction (IUGR), skeletal muscle fibers hav...

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Bibliographic Details
Main Authors: D. T. Yates, A. R. Macko, M. Nearing, X. Chen, R. P. Rhoads, S. W. Limesand
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2012/631038
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