Resveratrol protects pancreatic beta cell and hippocampal cells from the aggregate-prone capacity of hIAPP

Resveratrol protects pancreatic beta cell and hippocampal cells from the aggregate-prone capacity of hIAPP

Abstract Type 2 diabetes mellitus and Alzheimer’s disease, are two closely related pathological situations that are connected at the molecular level. In recent years, amylin, which is co-secreted with insulin, has been proposed for being a main actor in this context due to its capacity to form aggre...

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Bibliographic Details
Main Authors: Carlos González-Blanco, Ángela Cristina Lockwood, Beatriz Jiménez, Sarai Iglesias-Fortes, Patricia Marqués, Gema García, Ana García-Aguilar, Manuel Benito, Carlos Guillén
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Amylin
Beta cell
Beta-sheet-like aggregates
HT-22
Mitochondrial dynamics
Resveratrol
Online Access:https://doi.org/10.1038/s41598-024-78967-2
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