A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.

A transient homotypic interaction model for the influenza A virus NS1 protein effector domain.

Influenza A virus NS1 protein is a multifunctional virulence factor consisting of an RNA binding domain (RBD), a short linker, an effector domain (ED), and a C-terminal 'tail'. Although poorly understood, NS1 multimerization may autoregulate its actions. While RBD dimerization seems functi...

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Bibliographic Details
Main Authors: Philip S Kerry, Juan Ayllon, Margaret A Taylor, Claudia Hass, Andrew Lewis, Adolfo García-Sastre, Richard E Randall, Benjamin G Hale, Rupert J Russell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017946&type=printable
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