Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome
We report on a previously non-HIV-diagnosed, 47-year-old male diagnosed with diabetes mellitus (DM) and cryptococcal meningoencephalitis, who was referred to our institution for antifungal treatment. During the course of treatment, due to the development of refractory intracranial hypertension, Omma...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-11-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1444486/full |
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| _version_ | 1846151595838930944 |
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| author | Qinghua Chen Weitong Yu Xuyi Wang Chenxi Zhao Pin Wang Lin Sun Linlin Xu Yingying Xu |
| author_facet | Qinghua Chen Weitong Yu Xuyi Wang Chenxi Zhao Pin Wang Lin Sun Linlin Xu Yingying Xu |
| author_sort | Qinghua Chen |
| collection | DOAJ |
| description | We report on a previously non-HIV-diagnosed, 47-year-old male diagnosed with diabetes mellitus (DM) and cryptococcal meningoencephalitis, who was referred to our institution for antifungal treatment. During the course of treatment, due to the development of refractory intracranial hypertension, Ommaya reservoirs were employed for cranial pressure reduction. The patient gradually recovered during subsequent antifungal therapy; however, symptoms worsened in the third month of treatment, leading to consideration of post-infectious inflammatory response syndrome (PIIRS) on examination. Once diagnosed, the symptoms improved significantly after approximately 130 days of treatment with additional corticosteroids. |
| format | Article |
| id | doaj-art-1e28d34782fb42f487c56a54fb979284 |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-1e28d34782fb42f487c56a54fb9792842024-11-27T06:33:24ZengFrontiers Media S.A.Frontiers in Immunology1664-32242024-11-011510.3389/fimmu.2024.14444861444486Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndromeQinghua Chen0Weitong Yu1Xuyi Wang2Chenxi Zhao3Pin Wang4Lin Sun5Linlin Xu6Yingying Xu7The Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaThe Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaThe Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaThe Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaDepartment of Neurology Medicine, The Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaDepartment of Neurology Medicine, The Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaDepartment of Neurology Medicine, The Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaDepartment of Neurology Medicine, The Second Hospital of Shandong University, Cheeloo College of Medicine of Shandong University, Shandong University, Jinan, ChinaWe report on a previously non-HIV-diagnosed, 47-year-old male diagnosed with diabetes mellitus (DM) and cryptococcal meningoencephalitis, who was referred to our institution for antifungal treatment. During the course of treatment, due to the development of refractory intracranial hypertension, Ommaya reservoirs were employed for cranial pressure reduction. The patient gradually recovered during subsequent antifungal therapy; however, symptoms worsened in the third month of treatment, leading to consideration of post-infectious inflammatory response syndrome (PIIRS) on examination. Once diagnosed, the symptoms improved significantly after approximately 130 days of treatment with additional corticosteroids.https://www.frontiersin.org/articles/10.3389/fimmu.2024.1444486/fullcryptococcal meningoencephalitis (CM)diabetes mellitus (DM)ommaya capsulepost-infectious inflammatory response syndrome (PIIRS)human immunodeficiency |
| spellingShingle | Qinghua Chen Weitong Yu Xuyi Wang Chenxi Zhao Pin Wang Lin Sun Linlin Xu Yingying Xu Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome Frontiers in Immunology cryptococcal meningoencephalitis (CM) diabetes mellitus (DM) ommaya capsule post-infectious inflammatory response syndrome (PIIRS) human immunodeficiency |
| title | Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome |
| title_full | Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome |
| title_fullStr | Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome |
| title_full_unstemmed | Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome |
| title_short | Case report: A diabetic patient with cryptococcal meningoencephalitis complicated by post-infectious inflammatory response syndrome |
| title_sort | case report a diabetic patient with cryptococcal meningoencephalitis complicated by post infectious inflammatory response syndrome |
| topic | cryptococcal meningoencephalitis (CM) diabetes mellitus (DM) ommaya capsule post-infectious inflammatory response syndrome (PIIRS) human immunodeficiency |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2024.1444486/full |
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