Bullous pemphigoid and morphea: Coexistence or an incidental association
Morphea is considered an autoimmune disease because of reported autoantibody and autoimmune disease associations and is characterized by varying degrees of sclerosis, fibrosis, and atrophy in the skin and subcutaneous tissues and may involve muscle, bone, and brain. Plaque morphea is the most common...
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Indian Journal of Allergy Asthma and Immunology |
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| Online Access: | https://journals.lww.com/ijaa/fulltext/2024/38020/bullous_pemphigoid_and_morphea__coexistence_or_an.5.aspx |
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| _version_ | 1841526781341859840 |
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| author | Seema Rani Sweta Singh Arvind Ahuja |
| author_facet | Seema Rani Sweta Singh Arvind Ahuja |
| author_sort | Seema Rani |
| collection | DOAJ |
| description | Morphea is considered an autoimmune disease because of reported autoantibody and autoimmune disease associations and is characterized by varying degrees of sclerosis, fibrosis, and atrophy in the skin and subcutaneous tissues and may involve muscle, bone, and brain. Plaque morphea is the most common subtype occurring in adults followed by generalized and linear. The various inciting factors for morphea are trauma, radiation, drugs, and vaccination. The occurrence of bullous lesions in localized or systemic scleroderma is rare. Bullous pemphigoid (BP) is the most common autoimmune blistering skin disorder, in which autoantibodies target two hemidesmosomal components BP180 (Collagen XVII) and/or BP230. Although the etiology of BP remains uncertain, various diseases or treatments may be associated with the onset of BP, including neurological disorders, ultraviolet therapies, and drugs. In this report, we describe an old diabetic patient with a history of plaque morphea who developed BP while in remission from treatment. |
| format | Article |
| id | doaj-art-1dfe0087d3cf49898d6d9c37c59b608f |
| institution | Kabale University |
| issn | 0972-6691 2320-4745 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Allergy Asthma and Immunology |
| spelling | doaj-art-1dfe0087d3cf49898d6d9c37c59b608f2025-01-16T10:25:25ZengWolters Kluwer Medknow PublicationsIndian Journal of Allergy Asthma and Immunology0972-66912320-47452024-12-01382778010.4103/ijaai.ijaai_29_24Bullous pemphigoid and morphea: Coexistence or an incidental associationSeema RaniSweta SinghArvind AhujaMorphea is considered an autoimmune disease because of reported autoantibody and autoimmune disease associations and is characterized by varying degrees of sclerosis, fibrosis, and atrophy in the skin and subcutaneous tissues and may involve muscle, bone, and brain. Plaque morphea is the most common subtype occurring in adults followed by generalized and linear. The various inciting factors for morphea are trauma, radiation, drugs, and vaccination. The occurrence of bullous lesions in localized or systemic scleroderma is rare. Bullous pemphigoid (BP) is the most common autoimmune blistering skin disorder, in which autoantibodies target two hemidesmosomal components BP180 (Collagen XVII) and/or BP230. Although the etiology of BP remains uncertain, various diseases or treatments may be associated with the onset of BP, including neurological disorders, ultraviolet therapies, and drugs. In this report, we describe an old diabetic patient with a history of plaque morphea who developed BP while in remission from treatment.https://journals.lww.com/ijaa/fulltext/2024/38020/bullous_pemphigoid_and_morphea__coexistence_or_an.5.aspxautoimmune disorderbullous pemphigoidmorphea |
| spellingShingle | Seema Rani Sweta Singh Arvind Ahuja Bullous pemphigoid and morphea: Coexistence or an incidental association Indian Journal of Allergy Asthma and Immunology autoimmune disorder bullous pemphigoid morphea |
| title | Bullous pemphigoid and morphea: Coexistence or an incidental association |
| title_full | Bullous pemphigoid and morphea: Coexistence or an incidental association |
| title_fullStr | Bullous pemphigoid and morphea: Coexistence or an incidental association |
| title_full_unstemmed | Bullous pemphigoid and morphea: Coexistence or an incidental association |
| title_short | Bullous pemphigoid and morphea: Coexistence or an incidental association |
| title_sort | bullous pemphigoid and morphea coexistence or an incidental association |
| topic | autoimmune disorder bullous pemphigoid morphea |
| url | https://journals.lww.com/ijaa/fulltext/2024/38020/bullous_pemphigoid_and_morphea__coexistence_or_an.5.aspx |
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