Comparison of the Efficacy and Safety of
Direct Oral Anticoagulants and Warfarin
in Cirrhotic Patients: A Systematic Review
and Meta-Analysis

Comparison of the Efficacy and Safety of Direct Oral Anticoagulants and Warfarin in Cirrhotic Patients: A Systematic Review and Meta-Analysis

Objective Currently, there is limited evidence regarding the use of direct oral anticoagulants (DOACs) for patients with liver cirrhosis (LC). We performed a meta-analysis to compare the efficacy and safety of DOACs versus warfarin in this population. Methods We searched PubMed, Cochrane Library, We...

Full description

Saved in:

Bibliographic Details
Main Authors:	Chunwei Cheng MD, Juan Hua MD, Liang Xiong MD
Format:	Article
Language:	English
Published:	SAGE Publishing 2024-11-01
Series:	Clinical and Applied Thrombosis/Hemostasis
Online Access:	https://doi.org/10.1177/10760296241301402
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Direct Oral Anticoagulants Versus Traditional Anticoagulation in Cirrhotic Patients with Portal Vein Thrombosis: Updated Systematic Review
by: Xiulin Xiao M.S., et al.
Published: (2024-11-01)

Effectiveness and Safety of the Coadministration of Rifampin and Warfarin versus Direct Oral Anticoagulants: A Cohort Study
by: Ju-Chieh Wung, et al.
Published: (2024-01-01)

The Impact on Efficacy and Safety of Patients Receiving Oral Anticoagulant Medication (Warfarin) during the COVID-19 Pandemic
by: Ubonwan Sapoo, et al.
Published: (2024-07-01)

Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations
by: Sherif Elhosseiny, et al.
Published: (2019-01-01)

Risk of mortality between warfarin and direct oral anticoagulants: population-based cohort studies
by: Zixuan Wang, et al.
Published: (2024-12-01)

Safety and efficacy of direct oral anticoagulants in chronic kidney disease: a meta-analysis
by: Daniel Tham, et al.
Published: (2024-10-01)

Comparing rates of clinically relevant epistaxis in patients taking warfarin versus direct oral anticoagulants
by: Khristian S. Burke, et al.
Published: (2024-11-01)

Efficacy and Safety of New Oral Anticoagulants versus Warfarin in the Resolution of Atrial Fibrillation with Left Atrial/Left Atrial Appendage Thrombus: A Systematic Review and Meta-Analysis
by: Guan-lian Mo, et al.
Published: (2025-01-01)

Efficacy and Safety of Direct-Acting Oral Anticoagulants (DOACs) in the Overweight and Obese
by: Kimberley Doucette, et al.
Published: (2020-01-01)

Direct oral anticoagulants versus warfarin for venous thromboembolism prophylaxis in nephrotic syndrome patients: a retrospective study
by: Ahmed El-Bardissy, et al.
Published: (2025-01-01)

The Best Anticoagulation Strategy for Cirrhotic Patients who Underwent Splenectomy: A Network Meta-Analysis
by: Cheng Gong, et al.
Published: (2017-01-01)

Safety and Efficacy of Anticoagulation in Patients with Cirrhosis: A Meta-Analysis
by: Huan Chen, et al.
Published: (2021-01-01)

New warfarin anticoagulation management model after heart valve surgery: rationale and design of a prospective, multicentre, randomised trial to compare an internet-based warfarin anticoagulation management model with the traditional warfarin management model
by: Yan Li, et al.
Published: (2019-12-01)

Comparison of efficacy and safety of different anticoagulation regimens in plasma exchange: A systematic review and meta-analysis.
by: Song Ren, et al.
Published: (2024-01-01)

Mechanism of exacerbation of traumatic brain injury under warfarin anticoagulation in male mice.
by: Yuki Tatara, et al.
Published: (2024-01-01)

Prothrombin Complex Concentrate for Rapid Reversal of Warfarin Anticoagulation to Allow Neuraxial Blockade
by: Conor Skerritt, et al.
Published: (2014-01-01)

Comparison of the outcomes of warfarin therapy and economics by online and offline anticoagulation management models: protocol for a randomised controlled trial
by: Xiaotong Xia, et al.
Published: (2019-09-01)

Systemic Embolism and Clinically Significant Bleeding Events in Older Adults with Nonvalvular Atrial Fibrillation After Treatment with Direct Oral Anticoagulants and Warfarin: A Retrospective Cohort Study in Japan
by: Daichi Yaguchi, et al.
Published: (2024-11-01)

Evaluation of Anticoagulation Control among Patients Taking Warfarin in University of Gondar Hospital, Northwest Ethiopia
by: Zelalem Liyew, et al.
Published: (2021-01-01)

Comparison of Direct Oral Anticoagulants for Treatment of Cerebral Venous Thrombosis – A Retrospective Cohort Study
by: Paul Phan PharmD, et al.
Published: (2025-01-01)

Direct oral anticoagulants for stroke prevention and risk of bleeding
by: Tomoyuki Kawada
Published: (2025-02-01)

Predictors of direct oral anticoagulant concentrations in the trauma population
by: Laura Adams, et al.
Published: (2024-05-01)

Thrombolysis for ischaemic stroke despite direct oral anticoagulation
by: Ying Xian, et al.

Macro-vacuolar steatosis in a cirrhotic liver mimicking metastatic disease
by: Pietro Pitrone, MD, et al.
Published: (2025-02-01)

Efficacy and Safety of Rivaroxaban versus Warfarin for the Treatment of Acute Pulmonary Embolism: A Real-World Study
by: Yan Huang, et al.
Published: (2020-01-01)

Pharmacodynamic Modeling of Warfarin Dosing Algorithm for Cardiovascular Patients in Indonesia: A Tailored Method to Anticoagulation Therapy
by: Putriana NA, et al.
Published: (2025-01-01)

Real-world evidence of direct oral anticoagulants in patients with atrial fibrillation and cancer: A meta-analysis
by: Xiuying Li, et al.
Published: (2024-12-01)

DIRECT ORAL ANTICOAGULANTS IN PATIENTS AFFECTED BY MAJOR CONGENITAL THROMBOPHILIA
by: alessandra serrao, et al.
Published: (2019-06-01)

Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
by: Mahmoud Abdelnabi, et al.
Published: (2020-02-01)

Direct oral anticoagulants (DOACs): From the laboratory point of view
by: Margetić Sandra, et al.
Published: (2022-12-01)

Type 2 Diabetes, Atrial Fibrillation, and Direct Oral Anticoagulation
by: Dana Prídavková, et al.
Published: (2019-01-01)

Efficacy of CTPV for Diagnostic and Therapeutic Assessment: Comparison with Endoscopy in Cirrhotic Patients with Gastroesophageal Varices
by: Zijin Cui, et al.
Published: (2020-01-01)

Efficacy and safety of anticoagulants on venous thromboembolism: a systematic review and network meta-analysis of randomized controlled trials
by: Weijie Fu, et al.
Published: (2025-01-01)

Efficacy and safety of early anticoagulation in patients with acute ischemic stroke due to atrial fibrillation: a Meta-analysis
by: WANG Yunxiang, et al.
Published: (2024-02-01)

Influence of novel oral anticoagulants on anticoagulation care management
by: Janzic Andrej, et al.
Published: (2017-09-01)

To Measure or Not to Measure: Direct Oral Anticoagulant Laboratory Assay Monitoring in Clinical Practice
by: Tania Ahuja, et al.
Published: (2023-01-01)

Application of rapid genotyping of Warfarin individualized pharmacogenetic variants in Warfarin therapy
by: Defa Huang, et al.
Published: (2024-12-01)

Assessing the Comparative Efficacy and Safety of Warfarin and Rivaroxaban for Cancer Associated Thrombosis: Experience From a Resource Limited Setting
by: Abel Tenaw Tasamma, et al.
Published: (2025-01-01)

Factors related to the choice of warfarin for treating newly diagnosed nonvalvular atrial fibrillation are associated with safety outcomes during anticoagulation: A new‐user, active‐comparator, retrospective cohort study
by: Yoshiko Takagi, et al.
Published: (2024-12-01)

Safety and Efficacy of a Novel Hemostatic Powder in Total Knee Arthroplasty
by: Xinguang Wang MD, et al.
Published: (2024-12-01)