Genetic relationships between systemic lupus erythematosus and a positive antinuclear antibody test in the absence of autoimmune disease

Genetic relationships between systemic lupus erythematosus and a positive antinuclear antibody test in the absence of autoimmune disease

Objective We defined the genetic factors associated with a positive ANA test (ANA+) in the absence of autoimmune disease and tested the association with SLE.Methods Using a case-control design, we performed a genome-wide association study (GWAS) in individuals of European ancestry without an autoimm...

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Main Authors: Frank Mentch, Nancy J Olsen, Ge Liu, Wei-Qi Wei, Gul Karakoc, Nancy J Cox, Vivian Kawai, Charles Michael Stein, Atlas Khan, Jacy Zanussi, Mingjian Shi, Jonathan Mosley, Krysztof Kiryluk, Scott Hebbring, James Linneman
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/12/1/e001476.full
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